Construction and application evaluation of molecular model for predicting postoperative early recurrence risk of liver cancer

A technique for prognostic assessment and liver cancer, applied in the field of medical biological detection, can solve problems such as unsatisfactory prediction results
CN110577998APending Publication Date: 2019-12-17RENJI HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
RENJI HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
Publication Date
2019-12-17

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Abstract

The invention relates to construction and application evaluation of a molecular model for predicting postoperative early recurrence risk of liver cancer. Specifically, the invention found a biomarkerset which comprises various biomarkers for early postoperative recurrence of liver cancer, can be used for evaluating the risk of postoperative early recurrence of liver cancer patients, has the advantages of high sensitivity, high specificity and high accuracy, and has important application value. The invention further develops a risk prediction algorithm model and a device for postoperative early recurrence of liver cancer for the first time. The model can assist in clinically carrying out early prediction and early diagnosis on postoperative early recurrence of liver cancer. By implementingcloser postoperative follow-up visit and further adjuvant therapy, postoperative prognosis of liver cancer patients will be greatly improved.
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Description

technical field

[0001] The invention relates to the field of medical biological detection, in particular to the construction of a molecular model for predicting the early recurrence risk after liver cancer surgery and its application evaluation. Background technique

[0002] Hepatocellular carcinoma (HCC) is the most common primary liver cancer and the second leading cause of cancer-related death worldwide. At present, the diagnosis and operation techniques of liver cancer have gradually matured, but there are still a large number of patients with liver cancer who frequently relapse after surgery and further progress to advanced liver cancer, which ultimately leads to a poor overall prognosis of liver cancer. As we all know, the recurrence of liver cancer is divided into two types: early recurrence and late recurrence based on the 2 years after operation. Early recurrence is considered as "true recurrence", accounting for more than 70% of liver cancer recurrence, which leads...

Claims

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