Magnesium sulphate oral liquid

A magnesium sulfate oral liquid, the technology of magnesium sulfate, applied in the field of pharmaceutical preparations, can solve the problems of difficulty in successful coating, large dosage, low bitterness, etc., and achieve the effects of reducing bubble interference, reducing bitterness, and improving taste

Inactive Publication Date: 2020-01-07
高庆芬
View PDF2 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the dosage of oral preparations of magnesium sulfate is relatively large (generally greater than 25g), and it is often difficult to succeed by adopting the above-mentioned methods. The ions are too small to be successfully coated, so it is urgent to provide a magnesium sulfate oral solution with a lower bitter taste

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Magnesium sulphate oral liquid
  • Magnesium sulphate oral liquid
  • Magnesium sulphate oral liquid

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] The magnesium sulfate oral solution includes the following components: 5 g of magnesium sulfate, 0.01 g of sucralose, 0.01 g of mint essence, 94.78 g of water, 0.1 g of simethicone emulsion (40 mg / ml), and 0.1 g of sodium carboxymethylcellulose.

Embodiment 2

[0025] The magnesium sulfate oral solution includes the following components: 40g of magnesium sulfate, 1g of sucralose, 1g of orange essence, 48g of water, 5g of simethicone, and 5g of sodium carboxymethylcellulose.

Embodiment 3

[0027] The magnesium sulfate oral solution includes the following components: 10 g of magnesium sulfate, 0.05 g of sucralose, 0.05 g of strawberry essence, 88.9 g of water, 0.5 g of simethicone emulsion (40 mg / ml), and 0.5 g of carboxymethyl cellulose.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses magnesium sulphate oral liquid. The magnesium sulphate oral liquid comprises the following raw materials in percentage by mass of 5%-40% of magnesium sulphate, 0.01%-1% of a sweetening agent and 0.01%-1% of essence, wherein the essence is mint essence, strawberry essence, orange essence or cherry essence; an antifoaming agent is Simethicone emulsion; a thickening agent is sodium carboxymethyl cellulose, hydroxypropyl methylcellulose, carbomer or xanthan gum; and the sweetening agent is sucralose or Aspartame. The sweetening agent and the essence are added, so that the bitterness of the magnesium sulphate oral liquid can be reduced, and the mouth feel of the magnesium sulphate oral liquid can be improved.

Description

technical field [0001] The invention relates to the field of pharmaceutical preparations. More specifically, the present invention relates to a kind of magnesium sulfate oral liquid. Background technique [0002] Magnesium sulfate is a volumetric laxative, which is difficult to absorb in the gastrointestinal tract when taken orally, which increases the osmotic pressure in the intestinal cavity and stimulates the secretion of intestinal juice. At present, volumetric laxatives are often used in clinical bowel preparation, including mannitol, magnesium sulfate, sodium phosphate, polyethylene glycol electrolytes, etc. Mannitol significantly stimulates the gastrointestinal tract, and can produce flammable gases such as methane under the action of intestinal bacteria, which may cause a risk of gas explosion during high-frequency electrosurgery. A number of studies have confirmed that oral magnesium sulfate solution has good bowel preparation effect and less side effects, and can...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/06A61K9/08A61K47/26A61K47/46A61K47/34A61P1/10A61K49/00
CPCA61K9/0095A61K33/06A61K47/26A61K47/34A61K47/46A61K49/00A61P1/10
Inventor 吴诚
Owner 高庆芬
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products