Traditional Chinese medicine hydrogel patch capable of treating chemotherapeutic phlebitis, and preparation method thereof
A technology of chemotherapeutic phlebitis and hydrogel patch, which is applied in the direction of medical formula, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., which can solve inconvenient use, inaccurate dosage, and greasy skin To achieve better effect, comfortable application and suitable stickiness
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Embodiment 1
[0025] Example 1: A traditional Chinese medicine hydrogel patch for treating chemotherapeutic phlebitis, which has the following preparation methods:
[0026] (1) First weigh 150 g of Sargentodoxa cuneata, 150 g of Angelica dahurica, 150 g of rhubarb, 250 g of Fritillaria vulgaris, 40 g of woody, 150 g of cork, 10 g of frankincense, 10 g of myrrh, 5 g of borneol, and menthol 4 g, of which frankincense, myrrh, borneol, and menthol are ground into fine powder for later use; add 8000 mL of 80% ethanol after mixing the rest of the drugs, soak for 0.5 h, heat and reflux for extraction 3 times, 1.5 h each time, filter and combine Extract the liquid three times, recover the ethanol under reduced pressure, and concentrate it into a thick ointment with a relative density of 1.1, frankincense, myrrh, borneol, and menthol crushed fine powder, and add it to the concentrated liquid to obtain the active ingredients of the raw material;
[0027] (2) Take 200g of the active ingredient of the bulk ...
Embodiment 2
[0064] Example 2: A traditional Chinese medicine hydrogel patch for the treatment of chemotherapeutic phlebitis, 250 g of Sargentodoxa cuneata, 250 g of Angelica dahurica, 250 g of rhubarb, 500 g of Fritillaria vulgaris, 50 g of woody, 250 g of cork, and 20 frankincense g. Myrrh 20 g, borneol 10 g, and menthol 10 g, of which frankincense, myrrh, borneol, and menthol are ground into fine powder for later use; the rest of the drugs are mixed and soaked in 8525 mL of 60% ethanol for 1 hour, heated and refluxed for extraction 2 After 1 hour each time, filter, combine the extracts twice, recover ethanol under reduced pressure, and concentrate it into a thick paste with a relative density of 1.15 to obtain the active components of the bulk drug.
[0065] (2) Take 400g of the active ingredient of the bulk drug obtained in step (1), add it to 4000g of glycerin, and mix thoroughly under the condition that the vacuum is not lower than -0.05MPa;
[0066] (3) Weigh 130g of polyacrylic acid / sod...
Embodiment 3
[0070] Example 3: A traditional Chinese medicine hydrogel patch for the treatment of chemotherapeutic phlebitis, 50 g of Sargentodoxa cuneata, 50 g of Angelica dahurica, 50 g of rhubarb, 150 g of Fritillaria vulgaris, 5 g of woody, 50 g of phellodendron chinense, and frankincense 5 g. Myrrh 5 g, borneol 1 g, and menthol 1 g, among which frankincense, myrrh, borneol, and menthol are ground into fine powder for later use; the rest of the medicine is mixed and soaked in 4,500 mL of 90% ethanol for 1.5 hours, heated and refluxed for extraction 2 times, 3 hours each time, filter, combine the extracts for 3 times, recover the ethanol under reduced pressure, and concentrate it into a thick paste with a relative density of 1.2 to obtain the active ingredient of the bulk drug.
[0071] (2) Take 80 g of the active ingredient of the bulk drug obtained in step (1), add it to 1000 g of glycerin, and mix thoroughly under the condition of a vacuum degree of not less than -0.05 MPa;
[0072] (3) W...
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