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Method of forming an arteriovenous connection

An arteriovenous and venous technology, used in electrotherapy, hypodermic injection devices, artificial respiration, etc., can solve problems such as being unsuitable for dialysis

Inactive Publication Date: 2020-01-17
诺温图姆医药技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, up to 50% of AVFs created may never be suitable for dialysis

Method used

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  • Method of forming an arteriovenous connection
  • Method of forming an arteriovenous connection
  • Method of forming an arteriovenous connection

Examples

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Embodiment Construction

[0060] According to one aspect of the present invention, there is provided a method of forming an arteriovenous connection in a subject, the method comprising electrically stimulating a blood vessel comprising at least one artery of the subject and at least one vein of the subject, and subsequently fluidly connecting the at least one artery to at least one vein.

[0061] Methods according to embodiments of the present invention may improve (ie, reduce) the failure to mature (FTM) rate of vessels subjected to electrical stimulation and subsequently formed arteriovenous junctions. Electrical stimulation may be applied at a level and / or form sufficient to stimulate the subject's venous muscle pumps.

[0062] In a pilot study incorporating methods according to embodiments of the present invention, electrical stimulation was applied to a subject's blood vessels for 2 minutes using a first electrode positioned on the thenar eminence of the subject and a second electrode positioned i...

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Abstract

A method of forming an arteriovenous connection in a subject, comprising electrically stimulating vessels including at least one artery of the subject and at least one vein of the subject, and subsequently fluidly connecting the at least one artery to the at least one vein.

Description

technical field [0001] The present invention relates to a method of forming an arteriovenous connection in a subject, wherein such a connection may be performed, for example, prior to hemodialysis. Background technique [0002] Vascular access is required for hemodialysis treatment. In particular, vascular access allows for the removal and return of blood during hemodialysis, where the blood is passed through a filter (ie, a dialyzer) after it is removed from a subject and before it is returned to the subject. Vascular access allows a continuous flow of large volumes of blood to circulate through the filter (usually about 1 pint of blood per minute). [0003] A vascular access can be a simple intravenous catheter inserted into a subject's vein. Such arrangements are generally only for short-term use. Other types of vascular access can be created surgically and include arteriovenous connections between a subject's arteries and veins. The advantage of an arteriovenous conn...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N1/36A61N1/04
CPCA61N1/0456A61N1/0472A61N1/36021A61N1/36031A61N1/36034A61M1/3655A61M5/422A61M1/3661
Inventor 尼古拉斯·因斯通
Owner 诺温图姆医药技术有限公司