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Preparation method of lobeline hydrochloride injection

A technology of lobeline hydrochloride and injection, which is applied in the direction of making medicines into special physical or ingestible devices, etc., which can solve the problems that the preparation efficiency needs to be improved and the degree of automation is not high enough.

Pending Publication Date: 2020-01-24
北京市永康药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But at present the preparation method of lobeline hydrochloride injection still has the defects that the degree of automation is not high enough and the preparation efficiency needs to be improved.

Method used

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  • Preparation method of lobeline hydrochloride injection
  • Preparation method of lobeline hydrochloride injection

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Embodiment Construction

[0022] The present invention will be further described in detail below in conjunction with the accompanying drawings, so that those skilled in the art can implement it with reference to the description.

[0023] Such as figure 1 and figure 2 Shown, the invention provides a kind of preparation method of lobeline hydrochloride injection, comprising:

[0024]Step 1. Pre-place the solid raw material of Lobeline hydrochloride in an automatic weighing and feeding device 1, wherein the automatic weighing and feeding device 1 is connected to one end of the first transmission channel, and a feeding device 2 includes a feeding bin 17 and the feeding paddle 15, the feeding bin 17 has two areas adjacent to each other, the first valve 13 is arranged between the two areas of the feeding bin, and the feeding paddle 15 starts from one of the areas 11 The way to move to another area 12 is set inside the feeding bin, and the moving path of the feeding paddle is from the front end wall corres...

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Abstract

The invention discloses a preparation method of a lobeline hydrochloride injection, which comprises the following steps: a lobeline hydrochloride solid raw material is placed in an automatic weighingand feeding device in advance, and a material placing device comprises a feeding bin and a feeding poking sheet; the first metered solid raw material is conveyed into the feeding bin by adopting the automatic weighing and feeding device; a linear driving mechanism is adopted to drive the feeding poking piece to move from the front end wall to the rear end wall of the feeding bin, so that solid rawmaterials are fed into a primary liquid preparation tank; a first liquid metering pump is adopted to convey the second metered water for injection from a liquid storage tank to the primary liquid preparation tank, so that primary prepared liquid is prepared; the activated carbon is conveyed into the primary liquid preparation tank through activated carbon storage equipment; the liquid in the primary liquid preparation tank is filtered through a filter by adopting a second liquid metering pump, and then the filtered liquid is conveyed into a secondary liquid preparation tank; and a third liquid metering pump is adopted to convey the water for injection in the liquid storage tank into the secondary liquid preparation tank. According to the invention, the preparation efficiency and the preparation precision of the lobeline hydrochloride injection are improved to a great extent.

Description

technical field [0001] The invention relates to a preparation method of lobeline hydrochloride injection. Background technique [0002] Lobeline hydrochloride injection is used for respiratory depression and neonatal asphyxia caused by various reasons. It can stimulate carotid sinus and aortic body chemoreceptors (both N1 receptors), and reflexively excite the respiratory center to accelerate breathing, but has no direct excitatory effect on the respiratory center. It also has a reflex excitatory effect on the vagus nerve center and vasomotor center at the same time; it excites the autonomic ganglion first and then blocks it. However, the current preparation method of lobeline hydrochloride injection still has the defects that the degree of automation is not high enough and the preparation efficiency needs to be improved. Contents of the invention [0003] An object of the present invention is to solve at least the above problems and / or disadvantages and to provide at le...

Claims

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Application Information

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IPC IPC(8): A61J3/00
CPCA61J3/00
Inventor 高树庄左钰李玉会
Owner 北京市永康药业有限公司
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