Specific gene sequence of streptococcus anginosus, and detection primer and application of specific gene sequence
A specific gene, streptococcus technology, which is applied in the field of its detection primer, the specific gene sequence of Streptococcus pharyngitis, can solve the problems of cumbersome collection of exfoliated cytology, difficult to obtain satisfactory specimens, and few clinical applications.
Pending Publication Date: 2020-03-10
SHENZHEN HUADA GENE INST
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Problems solved by technology
[0003] The traditional screening methods for colorectal cancer are mainly colonoscopy, in addition to biopsy and exfoliative cytology. , less clinical application
Method used
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[0045] This example mainly focuses on the specific gene sequence screened by Streptococcus anginosus. The specific sequence is shown in SEQ ID NO:1-7 in Table 1.
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The invention discloses a specific gene sequence of streptococcus anginosus, and a detection primer and application of the specific gene sequence. The specific gene sequence disclosed by the inventionis selected from any one of sequences of SEQ ID NO:1-7 shown in the description. The primer comprises sequences of SEQ ID NO:10 and SEQ ID NO:11. The invention verifies relevance of the streptococcusanginosus and colorectal cancer, therefore, by detecting specific genes of the streptococcus anginosus in an intestine track, early-stage detection on occurrence and development of the colorectal cancer and in-time interference treatment can be achieved.
Description
Technical field [0001] The invention relates to the technical field of intestinal microbial detection, in particular to a specific gene sequence of Streptococcus pharyngitis, its detection primer and its application. Background technique [0002] According to statistics, colorectal cancer (CRC) ranks third in the incidence of various cancers, and the fatality rate ranks fourth, with nearly 55% of cases occurring in more developed countries. The incidence is lower in people younger than 40 years old, but the incidence gradually increases with age. It is generally believed that the westernization of eating habits will increase the incidence of CRC, but the current incidence in the United States and other high-income countries has remained stable or even decreased, which is speculated to be related to the increase in sigmoidoscopy and colonoscopic polypectomy. Colorectal cancer is also one of the most preventable tumors. The medical community believes that colorectal cancer is the ...
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Login to View More IPC IPC(8): C12Q1/689C12Q1/04C12Q1/6851C12N15/11C12R1/46
CPCC12Q1/689C12Q1/6851C12Q2531/113
Inventor 李南南揭著业易吉吴逵朱师达贾慧珏仝欣罗慧娟陈小芳
Owner SHENZHEN HUADA GENE INST