Solid nuclear magnetic resonance quantitative detection method and device based on successive cross polarization

Abstract

The invention provides a solid nuclear magnetic resonance quantitative detection method and device based on successive cross polarization. The method comprises the steps of determining a to-be-detected sample in a solid nuclear magnetic resonance spectrometer based on a preset pulse sequence to obtain a spectrogram of the to-be-detected sample, wherein the pulse sequence comprises a plurality of first pulse units and a second pulse unit, and the first pulse units are used for increasing enhancement coefficients of signals of 13C nucleuses located in different groups in the to-be-detected sample; and the second pulse unit is used for fixing a magnetization vector of a 1H nucleus of the to-be-detected sample in the magic angle direction, carrying out cross polarization on the 1H nucleus andthe 13C nucleus of the to-be-detected sample, and calculating the proportion of each group in the to-be-detected sample according to the spectrogram of the to-be-detected sample. According to the scheme, the second pulse unit fixes the magnetization vector of the 1H nucleus in the to-be-detected sample in the magic angle direction, so that the T1[rho]H of the 1H nucleus in the to-be-detected sample is prolonged, and the effect of improving the accuracy of quantitative detection is achieved.

Description

technical field [0001] The invention relates to the technical field of nuclear magnetic resonance, in particular to a solid-state nuclear magnetic resonance quantitative detection method and device based on successive cross-polarizations. Background technique [0002] Solid-state nuclear magnetic resonance quantitative detection technology is a technology used to quantitatively analyze the structure and components of solid samples. This technique is mainly to determine the initial spectrum of the sample to be analyzed by transmitting a preset pulse sequence to the solid sample to be analyzed, perform Fourier transformation on the initial spectrum, and obtain the processed spectrum by phase correction and baseline correction. , and finally integrate the peaks of each group in the processed spectrum to determine the proportion of each group or component in the sample to be analyzed. [0003] Among the existing solid-state NMR quantitative detection techniques, the most conven...

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Problems solved by technology

[0004] Based on the above-mentioned shortcomings of the prior art, the present invention provides a solid-state nuclear magnetic resonance quantitative detection method and device based on successive cross-polarizations to solve the problem of detecting T 1ρ H Issues with poorer accuracy on shorter samples

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