Hair blacking composition based on gene recombinant protein Tat-hMsrA and application of hair blacking composition

A technology of genetic recombination and composition, which is applied in the direction of hair care, grooming preparations, skin care preparations, etc., can solve the problems of retention, storage and activity maintenance, and large-scale mass production, so as to improve the environment and better Black hair effect, easy to transport and store

Inactive Publication Date: 2020-05-08
WUHAN HUA PEPTIDE BIOLOGICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, at present, the preparation of the above-mentioned proteins only stays in the laboratory stage, and large-scale mass production is difficult. Moreover, it is very difficult to preserve and maintain their activity when they are specifically applied in the field of cosmetics or pharmaceuticals.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] (1) Configuration of the recombinant protein Tat-hMsrA: mix 1 part of trehalose and 0.5 part of the recombinant protein Tat-hMsrA, mix well, then add 0.4 parts dropwise to the mixture, and mix well to obtain the recombinant protein Tat - hMsrA configuration solution.

[0032] (2) The configuration of the traditional Chinese medicine composition: mix uniformly according to 5 parts of Polygonum multiflorum extract, 2 parts of black sesame extract, 3 parts of ginger extract, 3 parts of Gastrodia elata extract, 1.4 parts of ginseng extract, and 5 parts of Chuanxiong extract to obtain Traditional Chinese medicine composition configuration liquid.

[0033] (3) Preparation of the composition: Add the preparation liquid of the gene recombinant protein Tat-hMsrA into the preparation liquid of the traditional Chinese medicine composition, oscillate and mix, and shake well to obtain the finished UFA composition.

Embodiment 2

[0035](1) Configuration of the recombinant protein Tat-hMsrA: mix 2 parts of trehalose and 1.5 parts of the recombinant protein Tat-hMsrA, mix well, then add 0.6 parts dropwise to the mixture, and mix well to obtain the recombinant protein Tat - hMsrA configuration solution.

[0036] (2) The configuration of the traditional Chinese medicine composition: according to 6 parts of Polygonum multiflorum extract, 3 parts of black sesame extract, 4 parts of ginger extract, 3 parts of Gastrodia elata extract, 1 part of ginseng extract, and 6 parts of Chuanxiong extract, mix evenly to obtain Traditional Chinese medicine composition configuration liquid.

[0037] (3) Preparation of the composition: Add the preparation liquid of the gene recombinant protein Tat-hMsrA into the preparation liquid of the traditional Chinese medicine composition, oscillate and mix, and shake well to obtain the finished UFA composition.

Embodiment 3

[0039] (1) Configuration of the recombinant protein Tat-hMsrA: mix 3 parts of trehalose and 2.5 parts of the recombinant protein Tat-hMsrA, mix well, then add 0.7 parts dropwise to the mixture, and mix well to obtain the recombinant protein Tat - hMsrA configuration solution.

[0040] (2) Configuration of traditional Chinese medicine composition: 7 parts of Polygonum multiflorum extract, 5 parts of black sesame extract, 5 parts of ginger extract, 2 parts of Gastrodia elata extract, 0.5 part of ginseng extract, 7 parts of Chuanxiong extract, angelica extract 1 part is mixed evenly to obtain a Chinese medicine composition preparation solution.

[0041] (3) Preparation of the composition: Add the preparation liquid of the gene recombinant protein Tat-hMsrA into the preparation liquid of the traditional Chinese medicine composition, oscillate and mix, and shake well to obtain the finished UFA composition.

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PUM

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Abstract

The invention relates to a hair blacking composition based on gene recombinant protein Tat-hMsrA. The hair blacking composition comprises the gene recombinant protein Tat-hMsrA and is prepared from the following components in parts by mass: 1-5 parts of trehalose, 0.5-5 parts of the gene recombinant protein Tat-hMsrA, 5-10 parts of a tuber fleeceflower root extract, 2-8 parts of a black sesame extract, 2-5 parts of a ginger extract, 1-3 parts of a rhizoma gastrodiae extract, 0.5-2 parts of a ginseng extract, 5-10 parts of a rhizoma chuanxiong extract and 0.4-1 part of a surfactant. The composition can be used for preparing a hair blacking lotion. The composition has the effects of resisting oxidation, scavenging free radicals, promoting growth of scalp and hair follicles and eliminating white hair, can better keep the activity of the gene recombinant protein Tat-hMsrA and has enormous market prospects.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and in particular relates to a black hair composition based on gene recombinant protein Tat-hMsrA and its application. Background technique [0002] A large number of modern neuroscience studies have shown that pathological damage mediated by oxygen free radicals is involved in the occurrence and development of a variety of major diseases of the nervous system. The brain's rich lipid content and relative lack of antioxidant enzyme levels make it more vulnerable to oxidative stress. Various factors (such as abnormally folded protein accumulation, ischemia-reperfusion injury, etc.) induce neurons to produce more reactive oxygen species (ROS) through pathways such as mitochondrial aerobic respiration, such as O 2- ., H 2 o 2 , OH and 1 o 2 , and the aging process is often accompanied by the weakening of ROS scavenging system (such as glutathione reduction system, superoxide dismutase, etc.), ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/64A61K8/66A61K8/60A61K8/9789A61K8/44A61K8/86A61K8/36A61Q5/12A61Q7/00A61Q17/00
CPCA61K8/64A61K8/66A61K8/60A61K8/9789A61K8/442A61K8/86A61K8/361A61Q5/12A61Q7/00A61Q17/005
Inventor 曾建华闫云云胡雪平
Owner WUHAN HUA PEPTIDE BIOLOGICAL TECH CO LTD
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