Alcoholism-relieving and liver-protecting composition and product
A technology of anti-alcoholic and liver-protecting composition, which is applied in the direction of drug combination, food ingredients containing natural extracts, dairy products, etc., and can solve problems such as confusion, irritability, central nervous system, and cardiovascular system damage
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[0086] The preparation of the anti-alcoholic and liver-protecting composition of the embodiment
[0087] raw material:
[0088] Pueraria root extract; (Jianshixing Biotechnology Research and Development (Shanghai) Co., Ltd., batch number 180622, the measured puerarin content is 8.3%);
[0089] Hovenia dulcis seed extract (Jianshixing Biotechnology Research and Development (Shanghai) Co., Ltd., batch number 180515, measured dihydromyricetin content 6.5%);
[0090] Taurine (Qianjiang Yongan Pharmaceutical Co., Ltd.);
[0091] Yeast powder (Lesaffre Management (Shanghai) Co., Ltd., product model: Lynside Forte BUS B vitamin-rich yeast);
[0092] Mixed probiotic powder (Danisco (China) Investment Co., Ltd.), each gram contains: Lactobacillus acidophilus NCFM, Lactobacillus paracasei Lpc-37, Bifidobacterium lactis Bi-07, Bifidobacterium lactis Bl-04 each 5 ×10 8 CFU, and Bifidobacterium lactis HN019 3×10 9 CFU.
[0093] Preparation: According to the daily dose of 70kg human b...
experiment example 1
[0115] Experimental Example 1 Behavioral Observation Experiment
[0116] experimental method:
[0117] After adaptive feeding for 3 days, 80 mice were randomly divided into 4 groups with 20 mice in each group. Food and water were fasted for 12 hours before the experiment. The experimental group was given different doses of anti-alcohol composition (respectively 1 times, 5 times and 10 times the human dose as the low dose, middle dose and high dose of the experiment) with a gavage dose of 2mL / 100g bw, and the control group was given distilled water , record the gavage time. After 30 minutes of administration, each group was fed with 0.19 mL / 10 g body weight of 56% (V / V) Red Star Erguotou, and the behavioral indicators of the mice were observed.
[0118] After the mice were ingested with white wine, they were immediately placed on a vertical metal net, and the climbing time of the mice on the metal net was recorded.
[0119] Continue to observe the activity of the mice, and ...
experiment example 2
[0126] Experimental Example 2 Determination of Ethanol Content
[0127] experimental method:
[0128] After 3 days of adaptive feeding, 40 rats were randomly divided into 4 groups with 10 rats in each group. Fasting 12h before the experiment, deprived of water. The experimental group was given different doses of anti-alcohol composition with 2mL / 100g bw gavage dose (respectively according to the animal pharmacology experiment drug conversion method, the dose conversion coefficient of 70kg human dose and 200g rat dose is 0.018, 1 times and 5 times the human dose and 10 times as the low dose, middle dose and high dose of the experiment), the control group was given distilled water, and the gavage time was recorded. After 30 minutes, each group was given 56% white wine by gavage with 1.33mL / 100g bw, and the gavage time was recorded. Blood was taken from the inner canthus at four time points of 0.5h, 1.0h, 2.0h and 3.0h after drinking, and the blood alcohol content was detected...
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