Nuclear magnetic resonance image classification method based on multi-strategy batch type active learning

An MRI, active learning technology, applied in neural learning methods, character and pattern recognition, recognizing medical/anatomical patterns, etc., can solve problems such as redundant information of samples, achieve high classification accuracy, and improve classification accuracy. , the effect of efficient diagnosis

Pending Publication Date: 2020-07-28
DALIAN MARITIME UNIVERSITY
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AI Technical Summary

Problems solved by technology

However, the traditional batch active learning method only uses a single uncertainty strategy or diversity strategy for screening when screening samples, resulting in a large amount of redundant information in the screened samples, resulting in additional labeling costs.

Method used

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  • Nuclear magnetic resonance image classification method based on multi-strategy batch type active learning
  • Nuclear magnetic resonance image classification method based on multi-strategy batch type active learning
  • Nuclear magnetic resonance image classification method based on multi-strategy batch type active learning

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Embodiment 1

[0074] Embodiment 1, a kind of nuclear magnetic resonance image classification method based on multi-strategy batch type active learning, comprises the following steps:

[0075] S1: Obtain the brain MRI images of three types of subjects with normal cognition, mild cognitive impairment and Alzheimer's disease as the original data set. The data set selects the data of 571 subjects, among which Alzheimer's disease There were 192 subjects, 171 subjects with mild cognitive impairment, and 208 subjects with normal cognition. The original data set was preprocessed to obtain an unlabeled sample set, an unlabeled validation set, and an unlabeled test set;

[0076] Wherein: preprocessing the original data set includes the following steps:

[0077] S1-1: Use SPM12 to preprocess the acquired nuclear magnetic resonance image, perform head correction, registration and segmentation operations on the NIFTI format nuclear magnetic resonance image, and obtain three images of gray matter, white...

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Abstract

The invention discloses a nuclear magnetic resonance image classification method based on multi-strategy batch type active learning and belongs to the field of intelligent medical diagnosis. The method comprises the following steps: obtaining a nuclear magnetic resonance image of the subject as an original data set; randomly selecting K samples from the unlabeled sample set; labeling, constructinga convolutional neural network model and a convolutional auto-encoder model; verifying the convolutional neural network model trained again by using the verification set; obtaining a trained convolutional neural network model; and inputting the unlabeled test set into the trained convolutional neural network model to obtain a final classification result of the nuclear magnetic resonance images ofthe three types of subjects with normal cognition, mild cognitive impairment and Alzheimer's disease, so that redundant information among the screened samples is relieved, and high-quality labeled samples are obtained. On the premise of ensuring high classification accuracy, the labeling cost of the nuclear magnetic resonance image is reduced, and a doctor is efficiently assisted in diagnosing the Alzheimer's disease.

Description

technical field [0001] The invention relates to the field of intelligent medical diagnosis, in particular to a method for classifying nuclear magnetic resonance images based on multi-strategy batch active learning. Background technique [0002] Alzheimer's disease (AD), also known as senile dementia, is an irreversible neurodegenerative disease of the brain. AD occurs frequently in the elderly, and patients are usually accompanied by symptoms such as memory loss and cognitive impairment. Generally, the diagnosis of Alzheimer's disease can be regarded as a classification problem, that is, to judge whether a subject belongs to the category of cognitive normal, mild cognitive impairment and Alzheimer's disease. [0003] At present, magnetic resonance imaging (Magnetic Resonance Imaging, MRI) has been widely used in the clinical diagnosis of Alzheimer's disease. MRI is a 3D image composed of a series of 2D slice images. It has the characteristics of high resolution, high contra...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06K9/62G06N3/04G06N3/08
CPCG06N3/088G06V2201/03G06N3/045G06F18/24G06F18/214
Inventor 王琳韩森
Owner DALIAN MARITIME UNIVERSITY
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