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Traditional Chinese medicine hydrogel eye pad and preparation method thereof

A technology of hydrogel and traditional Chinese medicine, which is applied in the direction of medical formulas, drug combinations, and medical preparations with non-active ingredients, etc. It can solve the problems that the application time cannot be reached, the application method is not firm, and the eye patch is easy to fall off. Achieve the effect of being conducive to transdermal absorption, high affinity, and enhancing the function of far and near adjustment

Pending Publication Date: 2020-08-07
范春 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the existing traditional Chinese medicine eye patch, non-woven fabric is used as the carrier, the non-woven fabric is soaked in the medicinal material extract, and the sticky paste of water is used to fix it around the eyes. , the eye patch is easy to fall off, and the scheduled application time cannot be reached, and the curative effect is poor

Method used

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  • Traditional Chinese medicine hydrogel eye pad and preparation method thereof
  • Traditional Chinese medicine hydrogel eye pad and preparation method thereof
  • Traditional Chinese medicine hydrogel eye pad and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] The present embodiment carries out the preparation of Chinese medicine hydrogel eye patch, comprises the following steps:

[0033] 1) In terms of parts by mass, 12 parts of pearls, 1 part of musk, 2 parts of Calculus Calculus, 2 parts of Mimenghua, 2 parts of Jinbuhuan and 1 part of saffron are placed in 100 parts of ethanol aqueous solution with a mass fraction of 75%, at 90 ° C Reflux extraction was carried out under reflux, and the reflux extraction was performed 3 times, and the time of each reflux extraction was 1 h to obtain a Chinese medicine extract, and then the Chinese medicine extracts extracted multiple times were combined, concentrated under reduced pressure, and concentrated Chinese medicine extracts were obtained;

[0034] 2) Dissolve 20 parts of hyaluronic acid and 20 parts of polyvinyl alcohol in 100 parts of deionized water, heat and stir at 90°C to 100°C until completely dissolved, and cool to obtain a colloid;

[0035] 3) Put the Chinese medicine ext...

Embodiment 2

[0056] In this example, the clinical curative effect of the traditional Chinese medicine hydrogel eye patch in Example 1, the traditional Chinese medicine hydrogel eye patch in Comparative Examples 1 to 7, and the non-woven fabric eye patch in Comparative Example 8 was tested, and the control group was the acupuncture treatment group.

[0057] The detection method is as follows: 500 cases of myopia patients (1000 eyes) are randomly divided into 10 groups of 50 cases (100 eyes in each group). The treatment group was applied with the traditional Chinese medicine hydrogel eye patch of Example 1, the comparison group was applied with the traditional Chinese medicine hydrogel eye patch of Comparative Examples 1 to 7 or the traditional Chinese medicine non-woven fabric eye patch of Comparative Example 8, and the control group was treated with acupuncture and moxibustion. Comparison of curative effect before and after treatment.

[0058] 1 clinical data

[0059] 1.1 General informat...

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Abstract

The invention belongs to the technical field of eye masks, and particularly relates to a traditional Chinese medicine hydrogel eye pad and a preparation method thereof. In the traditional Chinese medicine hydrogel eye pad, pearl, musk, calculus bovis, flos buddlejae, radix stephaniae tetrandrae and saffron crocus are matched, so the effects of activating blood, stimulating menstrual flow, clearingliver, improving eyesight, inducing resuscitation and freeing orifices are achieved; and a hydrogel is used for medicine loading, so the traditional Chinese medicine hydrogel eye pad is high in affinity, is easy to fit with the skin, high in moisture retention, large in drug loading capacity, high in transparency, good in air permeability, beneficial to transdermal absorption of drugs, capable ofguaranteeing drug effect, capable of being administrated through meridians and collaterals around the eyes, mainly used for treating myopia and relieving asthenopia and good in treatment effect on myopia, and the medicines contained in hydrogel are not prone to loss. Experimental results show that the traditional Chinese medicine hydrogel eye pad can restore the adjusting functions of the near vision and the distant vision of a patient, the diopter of the patient can adapt to the functions of the traditional Chinese medicine hydrogel eye pad autonomously, and the traditional Chinese medicinehydrogel eye pad can mainly treat myopia and relieve asthenopia.

Description

technical field [0001] The invention belongs to the technical field of eye patches, and in particular relates to a traditional Chinese medicine hydrogel eye patch and a preparation method thereof. Background technique [0002] Myopia is currently the most common eye disease worldwide. It is estimated that there are more than 1 billion myopia patients in the world. Due to the complexity of myopia, it is still in the stage of understanding. The physical optics concept of myopia is: when the eye adjustment is completely static, parallel light enters the eye and focuses on a refractive state before the sensory cell layer of the retina. Its clinical concept is: those with static refraction >=-0.25D. At present, myopia patients are mainly corrected by wearing concave lenses and orthokeratology lenses, but they cannot completely correct myopia fundamentally; they can also be treated by surgery, but there are many sequelae after surgery. The treatment of myopia currently lack...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/70A61K36/88A61K47/32A61K47/36A61P27/10A61K35/413A61K35/55A61K35/618
CPCA61K9/7023A61K47/32A61K47/36A61K35/618A61K35/55A61K35/413A61K36/56A61K36/59A61K36/88A61P27/10
Inventor 范春黄茜茜温柔
Owner 范春
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