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Shower gel containing ganoderma lucidum fruiting body spore powder fermentation liquor and preparation method of shower gel

A technology of Ganoderma lucidum fruiting body and spore powder, which can be applied to medical preparations containing active ingredients, preparations for skin care, pharmaceutical formulations, etc. Effect

Inactive Publication Date: 2020-12-04
上海洁士宝日化集团有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] From the above disclosure, it can be seen that the current Ganoderma lucidum extract uses organic solvent extraction or fermentation to extract active ingredients. Compared with the active ingredients obtained by organic solvent extraction, fermentation can degrade macromolecules to obtain smaller molecular weight, which is easier to be absorbed by the skin. However, it is difficult to extract the effective active ingredients of Ganoderma lucidum by the current fermentation method, which makes the Ganoderma lucidum extract prepared by the method have limitations in the use effect

Method used

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  • Shower gel containing ganoderma lucidum fruiting body spore powder fermentation liquor and preparation method of shower gel
  • Shower gel containing ganoderma lucidum fruiting body spore powder fermentation liquor and preparation method of shower gel
  • Shower gel containing ganoderma lucidum fruiting body spore powder fermentation liquor and preparation method of shower gel

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

[0055] The preparation method of the ganoderma fruiting body spore powder fermented liquid of this preparation example comprises the steps:

[0056] (1) Ganoderma lucidum fermentation substrate preparation: dry the fruiting body of Ganoderma lucidum, crush it through a 100-mesh sieve, add spore powder, the mass ratio of the fruiting body of Ganoderma lucidum and the spore powder is 1:1, and then add distilled water to prepare a 10% mass fraction The solution was sterilized at 121° C. for 15 minutes to obtain a sterilized ganoderma fermentation substrate;

[0057] (2) Strain activation: the strains were respectively inoculated into the culture medium by the plate marking method for cultivation, and the strains were selected from Bifidobacterium adolescentis CICC 6175, Bacillus natto CICC 10262, Bulgarian milk The mixed strains of Bacillus CICC20271 and Saccharomyces cerevisiae CICC 1252 are activated strains; the specific strains are activated as follows:

[0058] Bifidobacter...

experiment example

[0099] 1. Determination of Components of Ganoderma Lucidum Fruiting Body Spore Powder Fermentation Broth

[0100] The ganoderma lucidum fruiting body spore powder fermentation broth prepared in Preparation Examples 1-14 and Comparative Examples 1-4 were measured respectively, and the polysaccharide test method was referred to SNT4260; the BCA method was used to measure the protein polypeptide content; the Folin-Ciocalteu method was used to measure the polyphenol content; (NO 3 ) 3 -NaNO 2 The content of total flavonoids was determined by -NaOH method, and the results are shown in the table below.

[0101] table 3

[0102] group Polysaccharide (mg / mL) Peptide (mg / mL) Polyphenols (mg / mL) Total flavonoids (mg / mL) Preparation Example 1 3.17 4.24 0.057 0.033 Preparation example 2 3.12 4.18 0.053 0.031 Preparation example 3 3.08 4.15 0.051 0.029 Preparation Example 4 2.84 3.86 0.037 0.018 Preparation Example 5 2.76 3.79...

Embodiment 3

[0138] Comparing the results of Example 3 with Comparative Examples 5-8, it can be seen that the shower gel added with Ganoderma lucidum fermentation liquid has a positive effect on the improvement of the water content of the stratum corneum of the test subject under the condition that other raw materials remain unchanged, and adding Ganoderma lucidum fruiting body ratio The effect of ganoderma lucidum fermentation broth with the ratio of spore powder between (10-1):(1-10) is more obvious. However, if the Ganoderma lucidum fermented liquid is replaced with Ganoderma lucidum water extract, the water content of the cuticle will increase less.

[0139] 5. Evaluation of the soothing effect of the shower gel containing the spore powder fermented liquid of Ganoderma lucidum sporocarp of the present invention

[0140] 25 volunteers, aged 30-50 years old, half male and half male, were divided into 5 groups, 5 people in each group. Before the experiment, no drugs such as anti-inflamma...

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Abstract

The invention relates to shower gel containing ganoderma lucidum fruiting body spore powder fermentation liquor and a preparation method of the shower gel. The shower gel is prepared from the following raw materials in parts by weight of 39-58 parts of water, 8-15 parts of coconut oil acyl glutamic acid TEA salt, 5-8 parts of octyl / decyl glucoside, 0.5-2 parts of coconut oil acyl apple amino acidsodium, 2-5 parts of coconut oil glucoside, 3-5 parts of decyl glucoside and 10-20 parts of ganoderma lucidum fruiting body spore powder fermentation liquor, 5-10 parts of hemp leaf extract, 0.5-1.5 parts of PEG-120 methyl glucose dioleate, 0.5-1 part of glycolipid, and 0.5-1 part of eryngium maritimum callus culture filtrate. The shower gel is mild to skin while having strong foaming power, has multiple functions of resisting allergy, relieving, improving skin elasticity, moisturizing and the like, especially can significantly reduce skin sensitivity, and does not cause skin irritation even if the shower gel is used frequently.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and in particular relates to a shower gel containing ganoderma fruiting body spore powder fermented liquid and a preparation method thereof. Background technique [0002] Modern people use shower gel to take a bath very frequently, and some people even use it every day. However, many shower gels currently on the market are soap-based systems, or have added some irritating surfactant ingredients such as sulfates and sulfonates. These Shower gel is not gentle enough for the skin, and frequent contact with the skin is likely to damage the skin barrier, causing skin sensitivity, and it is even more irritating for people with sensitive skin. A kind of bath product that is mild to the skin, does not cause skin sensitivity, and is suitable for frequent use is currently rare on the market. [0003] Ganoderma lucidum, also known as Lin Zhongling, is umbrella-shaped in shape, with a kidney-shaped, semic...

Claims

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Application Information

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IPC IPC(8): A61K8/9728A61K8/60A61K8/46A61K8/44A61K8/99A61K8/9789A61Q19/10A61Q19/00A61Q19/02
CPCA61K8/44A61K8/466A61K8/602A61K8/99A61K2800/85A61Q19/00A61Q19/02A61Q19/10A61K8/9728A61K8/9789
Inventor 张启清盛俊娇余海励孙绪友
Owner 上海洁士宝日化集团有限公司
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