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Application of marsdenia tenacissima extract

A technology of clearing vine and extract, applied in the application field of clearing vine extract, can solve the problems of limiting the clinical expansion of anti-prostate cancer application of clearing vine extract, lack of molecular-level mechanism discussion and so on.

Pending Publication Date: 2020-12-04
GUANGXI MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Tongguanteng has extensive and definite anti-cancer effects, but unfortunately, there is no experimental research on the anti-prostate cancer cell level of Tongguanteng extract, and there is also a lack of molecular-level mechanism discussion, which limits to a certain extent Clinical expansion application of Tongguanteng extract against prostate cancer

Method used

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  • Application of marsdenia tenacissima extract
  • Application of marsdenia tenacissima extract
  • Application of marsdenia tenacissima extract

Examples

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Comparison scheme
Effect test

Embodiment 1

[0027] Application of the extract of Tengguanteng in the preparation of medicine for treating prostate cancer, the pharmaceutical preparation of Tengguanteng extract is injection preparation or tablet, specifically, the pharmaceutical preparation of Tengguanteng extract is Tengguanteng injection.

Embodiment 2

[0029] Application of Tengguanteng extract in the preparation of drugs for inhibiting the growth of prostate cancer cells PC3 and DU145, the pharmaceutical preparation of Tengguanteng extract is injection preparation or tablet, specifically, the pharmaceutical preparation of Tengguanteng extract is Tengguanteng injection liquid.

Embodiment 3

[0031] Application of Tengguanteng extract in the preparation of drugs for inhibiting the metastasis of prostate cancer cells PC3 and DU145, the pharmaceutical preparation of Tengguanteng extract is injection preparation or tablet, specifically, the pharmaceutical preparation of Tengguanteng extract is Tengguanteng injection liquid.

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Abstract

The invention discloses an application of a marsdenia tenacissima extract in preparation of a medicine for treating prostatic cancer, an application of the marsdenia tenacissima extract in preparationof a medicine for inhibiting cell growth of prostatic cancer PC3 and DU145, an application of the marsdenia tenacissima extract in preparation of a medicine for inhibiting cell migration of the prostatic cancer PC3 and DU145, an application of the marsdenia tenacissima extract in preparation of a medicine for inducing cell apoptosis of the prostate cancer DU145, an application of the marsdenia tenacissima extract in preparation of a medicine for inhibiting GSK-3[beta] / STAT3 signal axis, and an application of the marsdenia tenacissima extract in preparation of a medicine for up-regulating expression of Cytochrome C, Cleaved Caspase 3 and Cleaved Caspase 7. A marsdenia tenacissima extract medicine preparation is an injection preparation or a tablet. The application range of the marsdenia tenacissima extract is widened, and a new way is provided for application of the marsdenia tenacissima extract.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine. More specifically, the present invention relates to an application of the extract of Tengguanteng. Background technique [0002] Prostate cancer is one of the common malignant tumors of the genitourinary system in elderly men. Its incidence rate ranks first among male malignant tumors in developed countries in Europe and America, and its mortality rate ranks second, second only to lung cancer. With the aging of the population and the change of lifestyle, the prolongation of the average life expectancy of men and the improvement of medical diagnostic technology, the incidence and detection rate of prostate cancer in my country have shown a significant upward trend. Due to the insidious onset of prostate cancer, early clinical symptoms are often atypical. Therefore, most prostate cancers have metastasized or advanced when diagnosed. Based on my country's growing population b...

Claims

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Application Information

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IPC IPC(8): A61K36/27A61P35/00A61P35/04
CPCA61K36/27A61P35/00A61P35/04
Inventor 郭宏伟李小兰陈信张秋萍朱丹苏志恒兰太进谭雅文
Owner GUANGXI MEDICAL UNIVERSITY
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