A kind of skin barrier ointment dressing and preparation method thereof

A skin barrier and paste technology, applied in pharmaceutical formulations, bandages, drug delivery, etc., can solve the problems of difficult wounds, poor repair and moisturizing effect, low stability of cream dressings, etc., and achieves short polypeptide chains and good absorption. , The effect of promoting the restoration of skin barrier function

Active Publication Date: 2021-10-22
海南鸿翼医疗器械有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] There are many kinds of existing medical dressings. For the existing cream dressings, the ratio of the formula components of the milky mixing system is different, and various reasons such as different processes are used, resulting in the prepared cream body The stability of the dressing is low, the effect of repairing and moisturizing is poor, etc., it is difficult to effectively maintain a good wound sealing environment and maintain a stable wound repair environment

Method used

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  • A kind of skin barrier ointment dressing and preparation method thereof
  • A kind of skin barrier ointment dressing and preparation method thereof
  • A kind of skin barrier ointment dressing and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0022] A skin barrier ointment dressing, comprising the following raw materials in parts by weight: 2 parts of β-glucan, 1 part of sodium hyaluronate, 2 parts of ceramide, 5 parts of carbomer, 10 parts of polyethylene glycol-400, yeast 3 parts of polypeptides, 2 parts of glycerin, 2 parts of Tween 80, 4 parts of ethyl p-hydroxybenzoate, 3 parts of triethanolamine, 0.3 parts of fish bone essential oil and 200 parts of purified water, the molecular weight of sodium hyaluronate is 1.2×10 6 Da.

Embodiment 2

[0024] A skin barrier ointment dressing, comprising the following raw materials in parts by weight: 30 parts of β-glucan, 15 parts of sodium hyaluronate, 15 parts of ceramide, 10 parts of carbomer, 20 parts of polyethylene glycol-400, yeast 10 parts of polypeptides, 8 parts of glycerin, 6 parts of Tween 80, 20 parts of ethyl p-hydroxybenzoate, 8 parts of triethanolamine, 0.8 parts of fish bone essential oil and 600 parts of purified water, the molecular weight of sodium hyaluronate is 2.8×10 6 Da.

Embodiment 3

[0026] A skin barrier ointment dressing, comprising the following raw materials in parts by weight: 16 parts of β-glucan, 8 parts of sodium hyaluronate, 8 parts of ceramide, 7 parts of carbomer, 15 parts of polyethylene glycol-400, yeast 7 parts of polypeptides, 6 parts of glycerin, 4 parts of Tween 80, 12 parts of ethyl p-hydroxybenzoate, 5 parts of triethanolamine, 2 parts of fish bone essential oil and 400 parts of water, the molecular weight of sodium hyaluronate is 2.0×10 6 Da.

[0027] The preparation method of the skin barrier ointment dressing of the above-mentioned embodiments 1-3 is completed according to the following steps:

[0028] S1. Extraction of fish bone essential oil: select deep-sea tuna, remove the fish bones and put them in -25°C for quick freezing, take them out and crush them through a 230-mesh sieve before thawing to get fish bone slurry, and distilled water at a liquid-to-solid ratio of 17:1 Put it in a container for mixing, and use an ultrasonic ext...

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Abstract

The invention provides a skin barrier ointment dressing and a preparation method thereof, comprising the following raw materials in parts by weight: 2-30 parts of β-glucan, 1-15 parts of sodium hyaluronate, 2-15 parts of ceramide, carbomer 5-10 parts, 10-20 parts of polyethylene glycol-400, 3-10 parts of yeast polypeptides, 2-8 parts of glycerin, 2-6 parts of Tween 80, 4-20 parts of ethyl p-hydroxybenzoate, three 3-8 parts of ethanolamine, 0.3-0.8 parts of fish bone essential oil and 200-600 parts of water, the paste dressing of the present invention, its raw materials are all non-toxic natural materials, have excellent biocompatibility, biodegradability and good Excellent air permeability, can absorb a large amount of tissue exudate and have certain water retention performance, and can promote hemostasis and regeneration of native tissue, achieve continuous moisturizing, moisturizing and stable effects of the dressing, and provide a more stable repair screen for wounds closed environment.

Description

technical field [0001] The invention relates to the technical field of medical dressings, in particular to a skin barrier ointment dressing and a preparation method thereof. Background technique [0002] Medical plastic surgery can cause damage to the sebum membrane and stratum corneum on the surface of the skin, thereby affecting the skin barrier function, requiring care for the wound. The wound healing of human skin and the end of the year is a process that involves a variety of cells and their secreted products on the extracellular matrix. In the process of reconstruction and regeneration, maintaining the humidity of the wound surface and promoting skin cell proliferation and repair play a very important role in wound healing. [0003] There are many kinds of existing medical dressings. For the existing cream dressings, the ratio of the formula components of the milky mixing system is different, and various reasons such as different processes are used, resulting in the pr...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L26/00
CPCA61L26/0014A61L26/0019A61L26/0023A61L26/0047A61L26/0057A61L26/0061A61L26/0066A61L26/009A61L2300/204A61L2300/232A61L2300/236A61L2300/412A61L2400/04C08L5/02C08L5/08C08L33/02C08L71/02C08L89/00
Inventor 陈震王虹韵
Owner 海南鸿翼医疗器械有限公司
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