Anti-mite composition and application thereof

A composition and anti-mite technology, applied in the field of medicine and health, can solve the problems of remaining in soil, animal products or the environment, being difficult to decompose, entering into animals or humans, etc., and achieving resistance to drug resistance, efficient killing, No drug residue effect

Inactive Publication Date: 2020-12-08
北京皓尔生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the past century, chemical drugs have been widely used due to their high curative effect, fast action and convenient use. Most of the domestically used organic phosphorus, organic nitrogen, and organic chlorine drugs, but most of the chemically synthesized drugs have strong Chemical stability, not easy to decompose after use, remain in the soil, animal products or environment for a long time, enter the food chain directly or indirectly, enter animals or humans through bio-accumulation, and cause chronic or acute poisoning

Method used

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  • Anti-mite composition and application thereof
  • Anti-mite composition and application thereof
  • Anti-mite composition and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1～ Embodiment 4

[0018] Embodiment 1~Example 4 Preparation of a kind of anti-mite composition

[0019] Table 1 is the specific formulation of an anti-mite composition in Examples 1 to 4.

[0020] The concrete formula of a kind of anti-mite composition of table 1

[0021]

[0022]

[0023] The preparation method of A1~A4 in embodiment 1~embodiment 4:

[0024] (1) After cleaning and removing impurities from each traditional Chinese medicine, dry it at 40°C for subsequent use;

[0025] (2) adding 50% ethanol to Lilac, Artemisia annua and Thyme respectively, carrying out low-temperature extraction three times at 35-45°C, filtering, combining the filtrates, concentrating to an appropriate amount, and obtaining the extracts of each Chinese herbal medicine;

[0026] (3) Then add Sichuan pepper, white moss bark, cnidium, flavescens, atractylodes, lobelia, babe and woody respectively to deionized water for low-temperature extraction three times at 40-50°C, filter, combine the filtrates, and con...

Embodiment 5

[0028] Example 5 Preparation of an anti-mite composition water

[0029] Composition composition: A1 formula among the embodiment 1

[0030] Preparation method: Add 0.15 parts of EDTA-2Na into 83.85 parts of deionized water, stir until completely dissolved, then add 3 parts of A1, 8 parts of water-soluble olive oil and 5 parts of glycerin that have been mixed in advance, and stir to mix evenly.

Embodiment 6～ Embodiment 8

[0031] Embodiment 6~Example 8 Preparation of an anti-mite composition emulsion

[0032] Table 2 Anti-mite lotion formula

[0033]

[0034] Preparation method of anti-mite milk:

[0035] (1) According to the composition of the emulsions of Examples 6-8 and Comparative Example 1 in Table 2, heat the components of Phase A to 90-95° C. and stir to dissolve completely, and keep the temperature for 15 minutes;

[0036] (2) Mix and heat the components of Phase B to 90-95°C to dissolve completely, and keep the temperature constant for 15 minutes;

[0037] (3) Add phase A components to phase B and stir at the same time, and mix homogeneously at a speed of 3000r / min;

[0038] (4) Cool to 50°C under slow stirring, add phase C components and mix well;

[0039] (5) Add phase D to adjust the pH, and stir evenly to prepare anti-mite milks I, II, III and comparison milks.

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Abstract

The invention relates to an anti-mite composition and application thereof, and belongs to the technical field of medicine and health. The anti-mite composition is mainly prepared from the following components in parts by weight: 1 to 10 parts of antibacterial peptide, 1 to 10 parts of flos caryophylli extract and 1 to 10 parts of artemisia annua extract. The anti-mite composition provided by the invention is based on the pathogenesis and treatment principle of acariasis, natural active substances such as the antibacterial peptide, the flos caryophylli extract and the artemisia annua extract are selected, and the selected materials are scientific and reasonable in compatibility and have synergistic interaction; the anti-mite composition has the effects of quickly and efficiently killing mites, has a remarkable bacteriostatic or killing effect on dermatophytes, fungi, saccharomycetes, bacteria and the like, and also has excellent anti-inflammatory and itching relieving effects; and the anti-mite composition is natural in source, biodegradable, free of drug residues, unlikely to generate drug resistance, environment-friendly, safe and reliable.

Description

technical field [0001] The invention belongs to the technical field of medicine and hygiene, and in particular relates to an anti-mite composition and its application. Background technique [0002] Acaridosis is an ectoparasitic disease characterized by severe itching of the skin, exudative inflammation and high contact infection caused by carnivorous mites parasitizing on the body surface or in the epidermis of animals or humans. Our country folk is called " scabies mite ". It can be found in a variety of animals of all ages, and it is more common in pigs, sheep, rabbits, dogs, cattle and chickens. The disease has a wide range and is distributed worldwide. It can cause the production performance of sick animals and the quality of livestock products to decline, reduce digestion and absorption skills, become thin, and even cause individual or mass death of animals. It also threatens human health. [0003] The disease is a contact infection, occurs seasonally, and is charact...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/02A61K36/904A61P33/14A61K8/99A61K8/9794A61K8/9789A61K8/64A61K8/37A61K8/34A61Q19/00A01N65/46A01N65/36A01N65/28A01N65/08A01N65/12A01N63/20A01N37/46A01P7/02A61K31/045A61K35/744
CPCA61K38/02A61K35/744A61K36/61A61K36/282A61K36/758A61K36/75A61K36/234A61K36/284A61K36/34A61K36/904A61K36/285A61K31/045A61P33/14A61K8/99A61K8/64A61K8/9789A61K8/9794A61K8/375A61K8/34A61Q19/00A01N65/00A01N65/46A01N65/36A01N65/28A01N65/08A01N65/12A01N63/20A01N37/46
Inventor 刘春辉李自托
Owner 北京皓尔生物科技有限公司
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