Application of MANF protein
A protein, Sjögren's syndrome technology, applied in the field of biotechnology and medicine, can solve the problem that there is no research report on MANF protein
Active Publication Date: 2020-12-29
ANHUI MEDICAL UNIV
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At present, there is no research report on the a
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Embodiment 1
[0029] This embodiment provides the application of a MANF protein in the preparation of drugs for the treatment of Sjogren's syndrome, wherein Sjögren's syndrome in this embodiment includes one of primary Sjögren's syndrome or secondary Sjögren's syndrome, and this embodiment The MANF protein is encoded by the astrocyte-derived neurotrophic factor gene.
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The invention belongs to the field of biotechnology and medicines, discloses an application of MANF protein in preparation of a medicine for treating sicca syndrome. The application of the MANF protein in preparation of the medicine for treating the sicca syndrome is creatively provided, so that autoimmune diseases including primary sicca syndrome or secondary sicca syndrome can be treated; and the MANF protein has good clinical application prospects and can achieve obvious social benefits.
Description
technical field [0001] The invention belongs to the fields of biotechnology and medicine, and in particular relates to the application of a MANF protein in the preparation of medicines for treating Sjögren's syndrome. Background technique [0002] Sjogren's syndrome (SS) is an autoimmune disease that mainly affects the salivary glands and lacrimal glands, manifested as dry mouth and eyes; it can also affect other organs such as the skin with multi-system changes; a large number of lymph nodes can be seen in the affected organs Cell infiltration, a variety of autoantibodies can be detected in the serum, often accompanied by hyperimmunoglobulinemia. According to the cause of the disease, Sjogren's syndrome can be divided into two types: primary and secondary: primary Sjögren's syndrome is not associated with other connective tissue diseases; Sjögren's syndrome based on connective tissue diseases such as systemic lupus erythematosus, rheumatoid arthritis, and systemic sclerosi...
Claims
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Login to view more IPC IPC(8): A61K38/18A61P37/02
CPCA61K38/185A61P37/02
Inventor 吴华勋魏伟周彤彤黄磊
Owner ANHUI MEDICAL UNIV
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