Application of MANF protein

Abstract

The invention belongs to the field of biotechnology and medicines, discloses an application of MANF protein in preparation of a medicine for treating sicca syndrome. The application of the MANF protein in preparation of the medicine for treating the sicca syndrome is creatively provided, so that autoimmune diseases including primary sicca syndrome or secondary sicca syndrome can be treated; and the MANF protein has good clinical application prospects and can achieve obvious social benefits.

Description

technical field [0001] The invention belongs to the fields of biotechnology and medicine, and in particular relates to the application of a MANF protein in the preparation of medicines for treating Sjögren's syndrome. Background technique [0002] Sjogren's syndrome (SS) is an autoimmune disease that mainly affects the salivary glands and lacrimal glands, manifested as dry mouth and eyes; it can also affect other organs such as the skin with multi-system changes; a large number of lymph nodes can be seen in the affected organs Cell infiltration, a variety of autoantibodies can be detected in the serum, often accompanied by hyperimmunoglobulinemia. According to the cause of the disease, Sjogren's syndrome can be divided into two types: primary and secondary: primary Sjögren's syndrome is not associated with other connective tissue diseases; Sjögren's syndrome based on connective tissue diseases such as systemic lupus erythematosus, rheumatoid arthritis, and systemic sclerosi...

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Problems solved by technology

At present, there is no research report on the application of MANF protein in Sjögren's syndrome

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