Application of 2, 3-indolequinone in preparation of medicine for treating or preventing atherosclerotic cardiovascular and cerebrovascular diseases
A technology for atherosclerosis, cardiovascular and cerebrovascular diseases, applied in the field of medicine
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[0042] The present invention will be further described below in conjunction with the accompanying drawings and specific embodiments, so that those skilled in the art can better understand the present invention, but the present invention is not limited thereto.
[0043] Pharmacological experimental data of 3-indolequinone in the treatment of atherosclerosis.
[0044] Which animal to choose as an AS animal model needs to be considered from the following points: (1) The physiological structure is similar to the human body, and it has the expected effect on drug treatment or other interventions; (2) The animal is easy to obtain and raise in large quantities, Appropriate size, short feeding cycle, strong reproductive ability, and low overall cost; (3) The animal model has good operability and repeatability, and is easy to obtain through food feeding or simple operations; (4) The animal model can maintain a stable AS state, to avoid repetition; (5) The AS plaques generated are simil...
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