The invention discloses a healthcare rice wine containing hawthorn fruits and coffee. The healthcare rice wine is composed of the following raw materials, by weight, 106-110 parts of rice, 8-10 parts of a hawthorn fruit, 6-7 parts of seaweed powder, 5-6 parts of coffee powder, 2-3 parts of Helianthus tuberosus, 3-4 parts of shaddock peel, 1-2 parts of lavender, 1-2 parts of common fenugreek seed, 1-2 parts of grape leaf, 4-5 parts of Radix Puerariae, 3-4 parts of Folium Perillae, 2-3 parts of purslane, 0.6-0.8 parts of citric acid and 10-13 parts of distiller's yeast. The healthcare rice wine containing hawthorn fruits and coffee produced in the invention breakthroughs the mouthfeel of a traditional rice wine, has a sweet and mellow fragrance, and has a very high healthcare value, and the seaweed powder can improve the human immunity, the anticancer activity and the antivirus activity. The polysaccharides of the seaweed powder can be combined with HIVs (human immunodeficiency viruses) to inactivate the HIVs in order to inhibit the virus replication and control AIDS; and the polysaccharides of the seaweed powder can also reduce the content of lipids causing atherosclerosis in the blood vessel, and treat cardiovascular and cerebrovascular diseases. The healthcare rice wine containing hawthorn fruits and coffee has the efficacies of appetite stimulating, digestion helping, blood circulation promoting, stasis eliminating, panting calming, phlegm reducing and the like, and is beneficial for the health of human bodies.