Composition containing litchi seed extract for preventing or treating fatty liver or obesity

A composition and fatty liver technology, applied in the direction of food ingredients containing natural extracts, drug combinations, medical preparations containing active ingredients, etc., can solve the problems of non-alcoholic fatty liver patients and achieve excellent active effects
CN102740871AInactive Publication Date: 2012-10-17YONSEI UNIV TECH HLDG
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
YONSEI UNIV TECH HLDG
Publication Date
2012-10-17
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention relates to a composition containing extracts of Litchi seed for preventing or treating fatty liver or obesity. The composition of the present invention may induce the reduction of body fat mass, intestinal fat mass, total cholesterol concentration, levels of C / EBPa and PPAR?2 which are important factors of nuclear transcription in generating fat tissue, and the expression amounts of the aP2 gene which is the target gene of C / EBPa and PPAR?2, and eventually activate the prevention or treatment of obesity. The composition of the present invention may inhibit the progression of fatty liver diseases and treat same by maintaining the morphological, structural, and physiological functions of the liver, in addition to having the effect of preventing the development said fatty liver diseases.; Moreover, the composition of the present invention may improve fat accumulation in liver tissue by reducing the lipid content level in the liver tissue, and may have the effects of preventing the development of fatty liver, inhibiting the progression or improving the condition of patients by normalizing liver function marker enzyme expression. In addition, the present invention provides preliminary data showing that Litchi seed extracts, as a medicinal material and food, are efficacious in preventing and treating fatty liver diseases.
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Description

【Technical field】

[0001] The present invention relates to a composition for preventing or treating obesity or fatty liver comprising a litchi seed extract, and a method for preventing or treating obesity or fatty liver comprising a step of administering the composition to a subject in need. 【Background technique】

[0002] According to the Korean Pharmacopoeia of Chinese Herbal Medicine (Crude Drugs) specification collection, litchi core (Litchi core) is the seed of Litchi (Litchi chinensis Sonnerat) belonging to Sapindaceae (Sapindaceae). The scientific name is Litchi semen, also known as Dan Li core, There are different names for Lihe, Lizhi, Lizhihe, Zhihe, Liren and Lihe. The litchi core is oval-oval, slightly flattened on one side, with a length of 12mm-22mm and a diameter of 6mm-16mm. The surface is brownish-red or purple-brown, smooth and shiny, with slightly longitudinally wrinkled fine ripples, one end is round, and the texture is relatively hard. Moreover, it is t...

Claims

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