52results about How to "Help prevent" patented technology

The present invention relates to molecular immunology technology, and aims at screening out antigen epitope molecular simulation peptide capable of exciting human body's protective immunoreaction against tubercle bacillus, researching protective immunoreaction mechanism against tuberculosis, and further developing new type of concatenate polyepitope tuberculosis vaccine. The present invention provides one kind of antigen epitope molecular simulation peptide capable of exciting human body's protective immunoreaction against tubercle bacillus, and the peptide contains the amino acid sequence selected from SEQ ID Nos. 2, 5, 10, 12, 14 and 15. The present invention also provides the screening process and use of the peptide. The present invention may be used in preventing and controlling tuberculosis.

The invention relates to an application of nicotinamide riboside in preparing drugs for treating non-alcoholic steatohepatitis. According to the application, a non-alcoholic steatohepatitis animal model is adopted to prove that the nicotinamide riboside is capable of reducing the liver lipid content, the liver inflammations and the liver fibrosis degree of the animal model and prompt that the nicotinamide riboside can be applied to preparing the drugs for treating the non-alcoholic steatohepatitis. The application of the nicotinamide riboside is expanded, a new way is provided for treating the non-alcoholic steatohepatitis, and therefore, the non-alcoholic steatohepatitis can be prevented and prognosed favorably.

The invention discloses medicine application of fructus teminaliae billaricae extract and particularly relates to application of fructus teminaliae billaricae extract and fructus teminaliae billaricae polyphenol in hyperuricemia medicine preparing. The fructus teminaliae billaricae extract and the fructus teminaliae billaricae polyphenol have the effect of xanthine oxidase activity restraining, uric acid concentration in hyperuricemia model mouse blood can be effectively lowered, the effect of hyperuricemia treating is achieved, and meanwhile the good treating effect is achieved on metabolic diseases related to hyperuricemia, namely gout.

The invention discloses a real-time fluorescent quantitative PCR method used for detecting Mycobacterium tuberculosis. The method comprises the following steps: 1, collecting and processing a patient sputum sample; 2, extracting the DNA of the sample; 3, carrying out a real-time fluorescent quantitative PCR reaction of the DNA of the sample through treating the DNA of a standard strain as a positive control and disinfected water as a negative control; and 4, judging the detection result of the sample according to a Ct value obtained through the reaction, and calculating to obtain the copy number of the Mycobacterium tuberculosis in the sample. The invention also discloses a primer and a probe used in the detection method, and a kit containing the primer and the probe. The detection method has the advantages of simplicity, rapidness and high specificity, and can realize the rapid and quantitative detection of the Mycobacterium tuberculosis in clinic sputum samples, so the detection method is helpful for the prevention and the timely prevention of diseases.

The invention discloses a molecular marker for diagnosing and treating tumors. The molecular marker is a fused gene PLEKHA1-TACC2; and the fused gene simultaneously contains a part of sequences of a gene PLEKHA1 and a gene TACC2. The molecular marker disclosed by the invention is beneficial to early diagnosing and treating tumours, increasing the screening efficiency and reducing the screening cost; a direction is provided for individualized treatment; and the survival rate and the survival quality of patients are improved.

The invention discloses a feed additive capable of improving an edible value of chickens. The feed additive is prepared from the following substances: rhizoma atractylodis, pericarpium citri reticulatae viride, herba portulacae, radix astragali seu hedysari, radix glycyrrhizae, herba leonuri, agrimonia pilosa, herba clinopodii, radix paeoniae alba, fructus lycii, rhizoma dioscoreae, flos sophorae immaturus, herba siegesbeckiae, cornu cervi degelatinatum, black soybeans and modified attapulgite powder. The additive disclosed by the invention is mainly prepared from natural Chinese herbal medicine ingredients, so that any side effect on chicken products is not caused; a plurality of types of Chinese herbal medicine are reasonably matched so that all beneficial components can express the maximum effect; after the chickens eat the feed additive for long time, the morbidity of the chickens is greatly reduced, and the mouth feel of meat, the nutritive value and the yield are relatively improved; a lot of verification finds out that the chicken product raised by the additive can be used for effectively reducing hypertension, hyperlipemia and hyperglycemia; the prevention and treatment of gynecological diseases and age-related diseases can be facilitated, and the nourishing effect on pregnant and lying-in women and old people is relatively good.

The invention discloses pig feed with a disease prevention function. The pig feed is prepared from the following raw materials in parts by weight: 100 to 110 parts of rapeseed dreg meal, 50 to 60 parts of soybean meal, 50 to 60 parts of wheat meal, 70 to 80 parts of corn meal, 70 to 80 parts of pineapple leaf powder, 15 to 20 parts of chrysanthemum dreg meal, 10 to 12 parts of feeding stimulants and 10 to 12 parts of traditional Chinese medicine preparations; the feeding stimulant is prepared from the following raw materials in parts by weight: 3 to 4 parts of malt meal, 6 to 8 parts of folium artemisiae argyi powder, 2 to 3 parts of rhizoma cyrtomii powder, 3 to 4 parts of liquorice root powder, 2 to 4 parts of lotus seed powder, 1 to 2 parts of cordyceps militaris powder, 1 to 2 parts of rhizoma coptidis powder, 2 to 3 parts of herba elsholtziae powder, 6 to 8 parts of herba verbenae powder, 6 to 7 parts of hyssop powder, 5 to 8 parts of marjoram powder and 1 to 2 parts of broadleaf holly leaf powder; the traditional Chinese medicine preparation is prepared from the following raw materials in parts by weight: 1 to 2 parts of bamboo leaf powder, 3 to 6 parts of hawthorn powder, 1 to 2 parts of radix angelicae sinensis powder, 3 to 6 parts of common andrographis herb powder, 1 to 2 parts of arabian jasmine flower powder, 3 to 6 parts of spina date seed powder, 3 to 6 parts of cortex albiziae powder, 3 to 6 parts of lotus stalk powder and 1 to 2 parts of sophora alopecuroide powder. The pig feed capable of improving the pig disease resistance and achieving the disease prevention effect is prepared through steps of raw material mixing, decocting, pelletizing and the like.

The invention relates to a plant lactic acid product prepared by separating and deodorizing soybeans, walnuts and other high-quality vegetable proteins and performing natural fermentation with lactic acid bacteria, and a production process thereof. The process comprises the following steps: 1, mixing soybeans and walnuts, and performing pulp and dreg separation; 2, performing complete deodorization treatment on the mixed pulp; 3, adding lactic acid bacteria subjected to habituated culture for fermenting; 4, adding water and grinding; 5, grinding at a high speed; and 6, performing ultra-high temperature instant sterilization, cooling and packaging. According to the invention, the plant lactic acid product prepared by the method contains high proteins, multiple trace elements, vitamins, isoflavone and bifidus factors, does not contain cholesterol or animal fat and has a health-care effect. The drink does not contain precipitate, is not layered and has the shelf life of over three months.

The invention relates to a preparation method of a renewable electrochemical immunosensor which can be used for predicting and diagnosing a biomarker of acute coronary syndrome, namely a soluble CD40ligand (sCD40L), which belongs to the technical field of electrochemical detection. The method provided by the invention comprises the steps that a carboxyl-functionalized multi-walled carbon nanotube-polyethyleneimine-gold nanoparticle nanocomposite (c-MWCNTs-PEI-AuNPs) is used as a substrate material for immobilizing an sCD40L antibody, so as to capture the sCD40L; and then the sCD40L is quantitatively detected. Since the c-MWCNTs-PEI-AuNPs nanocomposite has the advantages of simple preparation, good electrical conductivity, good stability and large specific surface area, the nanocomposite can firmly immobilize a large number of antibodies and utilizes specific recognition of antibodies and antigens. The constructed electrochemical immunosensor has strong specificity. The method providedby the invention has the advantages of high sensitivity and specificity, convenience, quickness and regenerability, provides a new method for detecting the sCD40L, and provides useful information forclinical prediction and diagnosis of acute coronary syndrome.

The invention discloses a brown planthopper NlAtg1 gene and application thereof and an encoded protein and application thereof. The nucleotide sequence of the NlAtg1 gene is shown as SEQ ID NO: 1, themitochondrial structure and function of the brown planthopper can be influenced when the function of the gene is inhibited, so that the survival rate of the brown planthopper is reduced. The amino acid sequence of the protein encoded by the NlAtg1 gene is shown as SEQ ID NO: 2. According to the application of the NlAtg1 gene or protein, the NlAtg1 gene or protein can be used for developing a novel RNA insecticide in brown planthopper prevention and treatment or researching and developing a pesticide taking the NlAtg1 protein as a target. The RNA interference is successfully carried out on thegene; the result shows that the survival rate of pests is reduced; since RNA interference fragments can be specifically designed for species, the killing of non-target organisms is expected to be reduced while the pests are inhibited. The formed insecticide is an environment-friendly insecticide.

The invention provides a fast detecting and source-tracing method for cryptosporidium and giardia lamblia in urban sewage. The method comprises the following steps of: 1) collecting a proper amount of urban sewage, leaving the urban sewage for a while, abandoning sewage in the upper layer and collecting sewage in the lower layer; 2) repeating the step 1) to a certain water sample total amount; 3) centrifugalizing the collected water sample and collecting a precipitate; 4) extracting DNA in the precipitate; 5) performing PCR and sequencing on the extracted DNA to detect cryptosporidium and giardia lamblia in the urban sewage; and 6) comparing the sequence obtained in the step 5) with a sequence in the GenBank to determine the pest species or genotypes. By virtue of a method of performing PCR on the sewage after centrifugal precipitation, the invention provides the fast detecting and source-tracing method for cryptosporidium and giardia lamblia in the urban sewage, wherein the method is small in demand in sample volume, simple to operate, accurate in result, ideal in species-fixing and source-tracing effect and low in cost.

A membrane flux on-line prediction method for a membrane bioreactor process is provided. The method comprises: 1) establishing a membrane flux model of a membrane module in a membrane bioreactor process; 2) embedding the membrane flux model in a simulation platform of the membrane bioreactor process; and 3) taking the on-line collected influent data and operational data as an input value to the simulation platform, and obtaining a membrane flux prediction result according to the membrane flux model. According to the method provided by the present invention, the influent water and the operational conditions are combined to carry out membrane flux on-line prediction, it is verified that the membrane flux prediction result is consistent with the trend of the measured result, and the real operational condition of the site can be ideally approached, so that the degree of membrane fouling of the membrane module can be informed of in real time, the effect of membrane cleaning can be predicted, and the prevention of membrane fouling can be facilitated.

The invention, which belongs to the field of drugs or health care products, relates to application of rosa roxburghii or rosa roxburghii extract in preparation of a drug or health care product for preventing and treating pulmonary fibrosis. The invention provides application of rosa roxburghii or rosa roxburghii extract in preparation of a drug or health care product for preventing and treating pulmonary fibrosis. The in-vitro and in-vivo experiments prove that the rosa roxburghii can play an exact role in treating pulmonary fibrosis; toxicity to normal kidney cells is low; and the safety is high. Therefore, the pulmonary fibrosis can be prevented and a drug or health care product with good curative effect, low toxicity and low price for patients with pulmonary fibrosis can be provided. The application of rosa roxburghii or rosa roxburghii extract in preparation of a drug or health care product for preventing and treating pulmonary fibrosis has the remarkable clinical and social significance.

The invention relates to the technical field of VR evaluation, in particular to a cognitive function evaluation system and method based on virtual reality, and the system comprises a VR task module which is used for providing an immersive virtual reality game and a virtual scene of the virtual reality game; a man-machine interaction module which is used for realizing interaction between a user and a virtual scene; a game data acquisition module which is used for acquiring behavior data of a user in a virtual reality task induction state; a game data acquisition module which synchronously processes the behavior data, stores the behavior data and sends the behavior data to a data processing module; the data processing module which is used for preprocessing the behavior data and extracting characteristic parameters to obtain behavior data characteristic parameters; and an intelligent evaluation module which is used for training a machine learning regression model and performing score prediction of the cognitive function on the behavior data of the user to obtain a cognitive function evaluation result. According to the method, the cognitive function capability of the user is accurately evaluated through the behavior data in the virtual reality task induction state, the evaluation mode is convenient and easy to use, and the evaluation result is accurate.

The invention relates to a method for culturing microalgae and a method for producing grease. The method for culturing the microalgae comprises a step of harvesting the microalgae after over 10 days of photoautotrophic cultivation in an inoculated algae fluid, with a concentration of nitrogen fertilizer higher than 30 mmol/L, in terms of nitrogen atoms. The method provided by the invention can be used for culturing the microalgae efficiently at a large scale and low cost, can guarantee rapid growth of the microalgae, and enables the microalgae to have relatively high grease content.

The invention relates to the technical field of mask preparation, and particularly discloses an epidemic prevention traditional Chinese medicine mask. The mask contains the following traditional Chinese medicinal materials: agastache rugosus, elsholtzia, folium artemisiae argyi, raw rhizoma atractylodis, rhizoma kaempferiae and honeysuckle. The epidemic prevention traditional Chinese medicine maskis prepared from selected traditional Chinese medicines with the effects of resolving dampness with aromatics, dispelling turbidity, clearing away heat and toxic materials and the like according to the traditional Chinese medicine aromatic dirt-avoiding theory, the air disinfection effect can be enhanced, and qi of the fragrant traditional Chinese medicine pungent powder permeates into the Yingxiang acupoint and nasal mucosa to mobilize the external function of a body, so the mask is beneficial to resisting exogenous evil. Therefore, the effects of resisting viruses and enhancing the resistance of a human body are effectively achieved; the epidemic prevention traditional Chinese medicine mask effectively improves the effect of preventing the new coronal pneumonia of a wearer especially during the epidemic situation of the new coronal pneumonia.

The invention relates to selenium-rich food for promoting plumbum excretion and a preparation method thereof. The selenium-rich food can not only supplement selenium, but also take special physiological needs of a high lead level crowd into account, can be eaten for a long time, and can meet the special physiological needs of the high lead level crowd. The selenium content in each 100g of the selenium-rich food is greater than or equal to 25 micrograms, and the selenium-rich food can not only safely and effectively meet the needs of selenium by the high lead level crowd, but also effectively reduce the blood lead levels of the high lead level crowd, effectively promotes selenium to be discharged from the body, and improves complication caused by lead poisoning.

Space part S within a detecting chip 2 for single base substitution SNP and point mutation of genes where a plurality of gold electrodes 8 are formed in the base 7 of closed space part S, oligonucleotides 10 with different gene sequences are fixed to the gold electrodes 8, a common electrode 16 arranged not to contact the gold electrodes 8, are filled with DNA samples, voltage is applied between the common electrode 16 and the gold electrode 8, and current is measured to allow the double-stranded DNA to be detected and analyzed. It becomes possible to detect and analyze a large number of single base substitution SNP and point mutation for a plurality of DNA samples.

The invention relates to natural selenium-enriched food and a preparation method thereof. The selenium-enriched food comprises the following ingredients: 50-80 parts of selenium-enriched soybean, 180-250 parts of selenium-enriched black sesame, 200-240 parts of selenium-enriched walnut, 15-40 parts of selenium-enriched coix seed, 130-180 parts of selenium-enriched red date, 130-180 parts of selenium-enriched kelp, 10-30 parts of selenium-enriched fructus chaenomelis and 10-20 parts of selenium-enriched lemon. The selenium-enriched food is prepared by superhigh temperature instant sterilization, vacuum freeze drying and superfine grinding. A selenium content in the 100 g selenium-enriched food is greater than or equal to 20 micrograms, and the selenium-enriched food can safely and effectively meet the requirements of various populations on selenium, and exerts the effects of improving immune defense ability, skin quality and body functions of the various populations.

The invention discloses a method for greatly improving the quality of a scanning electron microscope sample of the salivary sheath of rice planthopper. The method comprises the following steps of: 1)taking a sample; 2) washing; 3) fixing; 4) dehydrating; 5) replacing ethanol; 6) drying; 7) pasting the sample and coating; 8) observing the sample. According to the method, a complete salivary sheathimage of the rice planthopper with a high resolution and a smooth surface is obtained by scanning electron microscope observation. A plurality of key steps in the preparation of the scanning electronmicroscope sample of the salivary sheath of the rice planthopper are improved, so that the problems of invisible samples, dry cracks, defects, fractures, unclear details and the like that are easy toappear in the scanning electron microscope observation of the salivary sheath of the rice planthopper are solved. The workload of relevant experimental personnel is reduced and the efficiency is improved.

The invention provides an oral cavity spray for clearing halitosis and a preparation method thereof. The oral cavity spray provided by the invention is prepared from the raw materials: epigallocatechin gallate, proanthocyanidins, citric acid, menthol, vitexin, notoginsenoside R1, xylitol, ethanol and sterile water. The oral cavity spray provided by the invention has relatively high inhibiting, killing and anti-adhesion actions on oral anaerobic bacteria such as fusobacterium nucleatum causing the halitosis, thus, the generation of sulfide gases is inhibited, and the oral cavity spray has a better clearing effect on the halitosis caused by oral cavity bacteria; the oral cavity spray can be used for reducing gum bleeding and refreshing breath.

A composite mineral feed additive comprises, by weight, 30 to 40% of microcrystalline kaolin, 35 to 40% of magnesian clay and 20 to 30 % of salt gypsum; when in use, the additive amount of the composite mineral feed additive is 4 to 7% of the weight of an animal feed. The composite mineral feed additive is rich in a variety of minerals needed for animal growth, and mineral soil also can adsorb organic nutrients, and has medicinal properties. The composite mineral feed additive can equivalently replace corn, wheat bran and other feeds for addition, and the feeding quality of animals can be improved.