Method for analyzing proportion of PD-L1 positive tumor cells in non-small cell lung cancer and storage equipment

A non-small cell lung cancer and PD-L1 technology, applied in the computer field, can solve the problems of low manual calculation efficiency, high threshold, and poor accuracy of pathologists, and achieve simplified machine learning pathological characteristics, time-consuming, learning and analysis difficulties big effect

Active Publication Date: 2021-02-05
FUZHOU MAIXIN BIOTECH CO LTD
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Problems solved by technology

[0007] Therefore, it is necessary to provide an analysis method for the proportion of PD-L1 positive tumor cells in non-small cell lung cancer, so as to solve the problems of low efficiency, poor accuracy and high threshold of manual calculation by pathologists in existing calculation methods

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  • Method for analyzing proportion of PD-L1 positive tumor cells in non-small cell lung cancer and storage equipment
  • Method for analyzing proportion of PD-L1 positive tumor cells in non-small cell lung cancer and storage equipment
  • Method for analyzing proportion of PD-L1 positive tumor cells in non-small cell lung cancer and storage equipment

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[0044] In order to explain in detail the technical content, structural features, achieved goals and effects of the technical solution, the following will be described in detail in conjunction with specific embodiments and accompanying drawings.

[0045] see figure 1 , in this embodiment, a method for analyzing the proportion of PD-L1 positive tumor cells in non-small cell lung cancer is specifically implemented as follows:

[0046] Firstly, the nouns that will appear in this embodiment are explained as follows:

[0047] TPS: Tumor Proportion Score, tumor cell positive proportion score.

[0048] In this embodiment, the specific marker is illustrated by PD-L1, and in other embodiments, it can be any other specific marker, and the tumor cell marker is illustrated by a cocktail mixed primary antibody, which is not limited. The following expands the specific description:

[0049] Step S101: Obtain the section to be stained. The details can be as follows: Take the preset number ...

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Abstract

The invention relates to the field of computers, in particular to a method for analyzing the proportion of PD-L1 positive tumor cells in non-small cell lung cancer and storage equipment. The method for analyzing the proportion of the PD-L1 positive tumor cells in the non-small cell lung cancer comprises the following steps: acquiring a section to be dyed; carrying out immunohistochemical stainingoperation on a tumor cell marker; carrying out immunohistochemical staining operation on a specific marker; obtaining a first region of interest, obtaining feature points, and calculating the total number of tumor cells according to the number of the feature points; obtaining feature points according to a second region of interest, and calculating the number of tumor cells stained by the specificmarker according to the feature points; and calculating the positive proportion fraction of the tumor cells according to the total number of the tumor cells and the number of the tumor cells dyed by the specific marker. In the whole process, a pathologist does not need to perform manual interpretation, so that the obtained result is more accurate and objective, and the efficiency is higher.

Description

technical field [0001] The invention relates to the field of computers, in particular to an analysis method and a storage device for the proportion of PD-L1 positive tumor cells in non-small cell lung cancer. Background technique [0002] Pathologists have a long training period, low income, and poor working environment. More importantly, they need a combination of a lot of knowledge, which requires both clinical knowledge and pathology training. The classification of pathology has a higher resolution under the microscope. There are tens of thousands of classifications of various diseases. It is necessary to remember the difference between classification and familiar classification. At the same time, it is necessary to distinguish and diagnose many similar diseases at the cellular level. A large amount of technical data and a large number of special techniques, and more importantly, a pathologist relies on the wisdom of the pathologist to transform the two-dimensional image ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/569C40B40/02
CPCG01N33/56966G16H30/40
Inventor 杨清海王小亚陈惠玲程本亮周洪辉吴楠楠
Owner FUZHOU MAIXIN BIOTECH CO LTD
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