Application of euphorbitin in preparation of medicine for preventing or treating alcoholic liver diseases

A technology for isozanflavin and alcoholic liver disease, applied in the field of medicine, can solve problems such as no reports, and achieve the effects of improving liver cell damage, reducing oxidative stress, and excellent activity
CN112353792AInactive Publication Date: 2021-02-12NANTONG UNIVERSITY
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
NANTONG UNIVERSITY
Publication Date
2021-02-12
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses an application of eupatorin in preparation of a medicine for preventing or treating alcoholic liver diseases, and belongs to the technical field of medicines. According to theinvention, an alcoholic liver disease animal model and a cell model are established through alcohol stimulation, the influence of eupatilin on alcohol-induced hepatocyte damage, oxidative stress and alcohol metabolic enzyme activity is observed, and research finds that eupatilin can significantly reduce alcohol-induced hepatocyte damage in both in-vivo and in-vitro experiments; oxidative stress isrelieved, the activity of alcohol metabolic enzymes is enhanced, and a new thought is provided for preventing and treating alcoholic liver diseases.
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Description

technical field

[0001] The invention belongs to the technical field of medicine, and specifically relates to the application of eupholzanthin in the preparation of drugs for preventing or treating alcoholic liver disease. Background technique

[0002] With the improvement of people's living standards, the number of people who drink alcohol is increasing day by day, and its incidence is also showing a trend of increasing year by year. It has become the second leading cause of liver damage besides viral hepatitis. Alcohol-induced liver damage will gradually evolve into alcoholic fatty liver, alcoholic hepatitis and liver fibrosis if it is not treated promptly and effectively. According to the statistics of the World Health Organization, more than 80% of heavy drinkers have a certain degree of fatty liver, 10-35% may develop alcoholic hepatitis, and 10-20% will develop liver fibrosis. Therefore, global alcoholic liver disease is a serious threat to human health, and strengthen...

Claims

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