Unlock instant, AI-driven research and patent intelligence for your innovation.

Production method for medical balloon

A manufacturing method and medical technology, applied in balloon catheters, catheters, coatings, etc., to achieve the effect of inhibiting delayed-type hypersensitivity

Pending Publication Date: 2021-03-30
ZEON CORP
View PDF6 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the case of using the latex composition specifically disclosed in Patent Document 1, although the occurrence of immediate hypersensitivity (Type I) caused by proteins derived from natural rubber can be prevented, on the other hand, since the ball as a dipped molded body The vulcanization accelerator contained in the capsule, there is a risk of allergic symptoms of delayed hypersensitivity (Type IV)

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Production method for medical balloon
  • Production method for medical balloon
  • Production method for medical balloon

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0190] Hereinafter, although an Example demonstrates this invention in detail, this invention is not limited to these Examples. In addition, unless otherwise indicated, the following "parts" are based on weight. In addition, various physical property measurements and evaluation tests were performed as follows.

[0191] Solid content concentration

[0192] A 2-g sample (weight: X2) was accurately weighed in an aluminum pan (weight: X1), and dried in a hot air dryer at 105° C. for 2 hours. Next, after cooling in a desiccator, the weight (weight: X3) of the aluminum pan was measured, and the solid content concentration was calculated according to the following calculation formula.

[0193] Solid content concentration (weight %)={(X3-X1) / X2}×100

[0194] Modification rate

[0195] by using 1 H-NMR measures the carboxy-modified conjugated diene polymer constituting the latex of the carboxy-modified conjugated diene polymer to determine the number of carboxyl groups in the ...

manufacture example 1

[0213] Production of Latex of Carboxyl-modified Synthetic Polyisoprene (A-1)

[0214] Synthetic polyisoprene with a weight average molecular weight of 1,300,000 (trade name "NIPOL IR2200L", manufactured by Nippon Zeon Co., Ltd., homopolymer of isoprene, cis-bonding unit content 98%) and cyclohexane Mix and dissolve by raising the temperature to 60° C. while stirring to prepare a synthetic polyisoprene cyclohexane solution (a) (solid content concentration: 8% by weight) having a viscosity of 12,000 mPa·s as measured by a B-type viscometer.

[0215] On the other hand, 20 parts of sodium abietic acid was added to water, and the temperature was raised to 60° C. to dissolve, thereby preparing an anionic surfactant aqueous solution (b) having a concentration of 1.5% by weight.

[0216] Next, the above cyclohexane solution (a) and the above anionic surfactant aqueous solution (b) were mixed in a weight ratio of 1:1.5 using a mixer (trade name "Multi-line mixer MS26-MMR-5.5L" , man...

manufacture example 2

[0222] Production of Latex of Carboxyl-modified Synthetic Polyisoprene (A-2)

[0223] Except that the amount of methacrylic acid used was changed from 3 parts to 5 parts, the same procedure as in Production Example 1 was carried out to obtain a latex of carboxyl-modified synthetic polyisoprene (A-2) having a solid content concentration of 55%. . The obtained latex of the carboxyl group-modified synthetic polyisoprene (A-2) was measured for the modification rate by the above-mentioned method, and the modification rate was 1 mol%.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
particle sizeaaaaaaaaaa
particle sizeaaaaaaaaaa
Login to View More

Abstract

To provide a production method for a medical balloon capable of reducing occurrence of symptoms of immediate allergy (type I) as well as delayed allergy (type IV). This production method has a step for molding, into a balloon shape, a composition containing a carboxy-modified conjugated diene polymer, a vulcanizing agent, and a xanthate compound. The step for molding the composition into a balloonshape includes a dip-molding step for immersing a balloon-shaped mold in the composition in the form of latex.

Description

technical field [0001] The invention relates to a manufacturing method of a medical balloon. Background technique [0002] For example, medical instruments having balloons, such as balloon catheters and endoscopes with balloons, are used for various treatments and examinations. As a medical balloon constituting a medical device having a balloon, a medical balloon obtained by dip-molding natural rubber latex is widely used. However, the latex of natural rubber contains proteins that cause symptoms of immediate hypersensitivity (Type I) in humans, so there are sometimes problems as a balloon that comes into direct contact with the human body. Therefore, studies have been made to use synthetic rubber latex instead of natural rubber latex as a material for medical balloons. [0003] For example, Patent Document 1 discloses a composition obtained by adding zinc oxide, sulfur, and a vulcanization accelerator to latex of synthetic polyisoprene as synthetic rubber as a composition...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61M25/10C08C19/28C08K5/38C08L13/02
CPCC08K5/38C08F279/02C08K3/06C08K3/22C08K2003/2296A61M25/1029A61L29/042C08L51/04C08F220/06C08L13/02B29C41/14C08C19/36
Inventor 泊晃平加藤慎二林实纱
Owner ZEON CORP