Preparation method of improved pulmonary cough pharmaceutical composition

A composition and drug technology, which is applied in the field of preparation of lung cough drug composition, can solve the problems of low production efficiency, low content of astragaloside IV, long drying time, etc.

Pending Publication Date: 2021-04-06
贵州健兴药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] In order to solve the above problems, the applicant improved the original preparation method through long-term exploration and testing, and solved the technical problems of too long drying time, low production efficiency and low content of astragaloside IV.

Method used

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  • Preparation method of improved pulmonary cough pharmaceutical composition
  • Preparation method of improved pulmonary cough pharmaceutical composition
  • Preparation method of improved pulmonary cough pharmaceutical composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Embodiment 1 preparation method

[0036] 1) Pre-treatment of Scutellaria baicalensis: select Scutellaria baicalensis herbs, wash, and bake in a tunnel oven at 90°C for 11.7 hours;

[0037] 2) Pre-treatment of 100 herbs: select 100 herbs, wash, cut, and bake in a tunnel oven at 90°C for 15.7 hours;

[0038] 3) Pre-treatment of sycamore root: select the medicinal material of sycamore root, wash it, and bake it in a tunnel oven at 90°C for 11.7 hours;

[0039] 4) Pre-treatment of gentian safflower: select gentian safflower medicinal materials, cut, screen, wash, and bake in a tunnel oven at 90°C for 11.7 hours;

[0040] 5) Grinding the pretreated medicinal materials in steps 1)-4) into fine powder, mixing evenly, adding 6 times the amount of 65% ethanol to reflux extraction for 3 times, each time for 1.5 hours, combining the extracts, filtering through filter cloth, and the filtrate for later use;

[0041] 6) The rest of the medicinal materials are decocted twice with bo...

Embodiment 2

[0042] Embodiment 2 preparation method

[0043] 1) Pre-treatment of Scutellaria baicalensis: select Scutellaria baicalensis herbs, wash, and bake in a tunnel oven at 90°C for 11.7 hours;

[0044] 2) Pre-treatment of 100 herbs: select 100 herbs, wash, cut, and bake in a tunnel oven at 90°C for 15.7 hours;

[0045] 3) Pre-treatment of sycamore root: select the medicinal material of sycamore root, wash it, and bake it in a tunnel oven at 90°C for 11.7 hours;

[0046] 4) Pre-treatment of gentian safflower: select gentian safflower medicinal materials, cut, screen, wash, and bake in a tunnel oven at 90°C for 11.7 hours;

[0047] 5) Grinding the pretreated medicinal materials in steps 1)-4) into fine powder, mixing evenly, adding 6 times the amount of 65% ethanol to reflux extraction for 3 times, each time for 1.5 hours, combining the extracts, filtering through filter cloth, and the filtrate for later use;

[0048]6) The rest of the medicinal materials are decocted twice with boi...

Embodiment 3

[0049] Embodiment 3 preparation method

[0050] 1) Pre-treatment of Scutellaria baicalensis: select Scutellaria baicalensis herbs, wash, and bake in a tunnel oven at 90°C for 11.7 hours;

[0051] 2) Pre-treatment of 100 herbs: select 100 herbs, wash, cut, and bake in a tunnel oven at 90°C for 15.7 hours;

[0052] 3) Pre-treatment of sycamore root: select the medicinal material of sycamore root, wash it, and bake it in a tunnel oven at 90°C for 11.7 hours;

[0053] 4) Pre-treatment of gentian safflower: select gentian safflower medicinal materials, cut, screen, wash, and bake in a tunnel oven at 90°C for 11.7 hours;

[0054] 5) Grinding the pretreated medicinal materials in steps 1)-4) into fine powder, mixing evenly, adding 6 times the amount of 65% ethanol to reflux extraction for 3 times, each time for 1.5 hours, combining the extracts, filtering through filter cloth, and the filtrate for later use;

[0055] 6) The rest of the medicinal materials are decocted twice with bo...

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Abstract

The invention relates to a preparation method of an improved pulmonary cough pharmaceutical composition, and the method comprises the following steps: drying scutellaria baicalensis, phoenix tree root, radix stemonae and gentiana rhodantha in an effective way, and carrying out alcohol extraction and the like, thereby solving the technical problems of overlong drying time, lower production efficiency and lower astragaloside content.

Description

technical field [0001] The invention relates to the field of medicine preparation, in particular to an improved preparation method of a lung cough medicine composition. Background technique [0002] Feilike Capsule and Feilike Mixture are products of Guizhou Jianxing Pharmaceutical Co., Ltd. They have the functions of relieving cough and relieving asthma, clearing heat and detoxifying, smoothing Qi and eliminating phlegm. It is used for coughing, asthma, excessive phlegm, shortness of breath, acute and chronic bronchitis, and emphysema with the above syndromes. During the production process, it was found that the water content of the medicinal materials fed was high, the drying time was too long, and the production efficiency was low; in addition, baicalin IV is an important active ingredient in the Feilike composition, and the existing preparation method has a low content of active ingredients, such as : [0003] [Chinese Invention] CN201910165098.9 Feilike Capsule Extrac...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/904A61P11/00A61P11/10A61P11/14
CPCA61K36/185A61K36/23A61K36/28A61K36/515A61K36/539A61K36/748A61K36/904A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61P11/00A61P11/10A61P11/14A61K2300/00
Inventor 孙小鹦廖萍廖伟廖忠
Owner 贵州健兴药业有限公司
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