Use of the linc00305 autoantibody detection reagent in the preparation of a lung cancer screening kit
An autoantibody and kit technology, which is applied in the field of preparing lung cancer screening kits, and achieves the effect of good clinical application prospects.
Active Publication Date: 2022-05-24
THE WEST CHINA SECOND UNIV HOSPITAL OF SICHUAN
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[0005] At present, a large number of studies have disclosed a variety of lung cancer markers. However, LINC00305 (longintergenic non-protein coding RNA 305) (gene ID: 221241, protein Q7Z4B0) has not been seen for the detection and diagnosis of lung cancer, and the detection of the expression level of LINC00305 The report of the kit
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Embodiment 2
[0044] Embodiment 2 The composition of the detection kit of the present invention and its use method
[0045] 1. Composition of the kit
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The invention relates to the field of in vitro diagnostic reagents, in particular to the use of the LINC00305 autoantibody detection reagent in the preparation of a lung cancer screening kit. The present invention finds for the first time that the autoantibody level of LINC00305 protein in serum of patients with lung cancer is significantly higher than that of healthy patients. The invention uses the reagent for detecting LINC00305 protein autoantibody to prepare a lung cancer screening kit, which can realize effective screening of lung cancer.
Description
technical field [0001] The invention belongs to the field of biological in vitro diagnostic reagents, in particular to the use of a LINC00305 autoantibody detection reagent in the preparation of a lung cancer screening kit. Background technique [0002] Lung cancer is one of the most common malignant tumors in the world, and its morbidity and mortality are increasing year by year. Currently, the morbidity ranks first in the world, and it is a serious threat to human health and life. Lung cancer is one of the malignant tumors with the fastest growing morbidity and mortality, and the greatest threat to the health and life of the population. In the past 50 years, many countries have reported that the morbidity and mortality of lung cancer have increased significantly. The incidence and mortality of lung cancer in men are the first among all malignant tumors, and the incidence and mortality of women are the second. [0003] Lung cancer is a kind of hidden disease, and it often ...
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IPC IPC(8): G01N33/574G01N33/564
Inventor 周斌张林王艳云宋雅平粟闵
Owner THE WEST CHINA SECOND UNIV HOSPITAL OF SICHUAN