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Traditional Chinese medicine composition as well as application and preparation thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition and its use and preparation, to prevent and treat atherosclerotic plaque caused by "pulse phlegm nucleus", which can solve the problem of inability to bring therapeutic effect to patients, failure to Problems such as the formation of traditional Chinese medicine products

Inactive Publication Date: 2021-08-27
DONGZHIMEN HOSPITAL OF BEIJING UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Searching the literature, the theory of "pulse generating phlegm core" is used to treat diseases such as atherosclerotic plaques, and most of them are based on clinical prescriptions, which have not been formed into traditional Chinese medicine products. Therefore, they cannot bring therapeutic effects to many patients.

Method used

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  • Traditional Chinese medicine composition as well as application and preparation thereof
  • Traditional Chinese medicine composition as well as application and preparation thereof
  • Traditional Chinese medicine composition as well as application and preparation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0075] Ganoderma lucidum 2000g, Scrophulariaceae 1000g, Salvia miltiorrhiza 1000g, Coptidis 600g, Fritillaria 600g, raw oyster 600g, angelica 600g, frankincense 400g, myrrh 400g.

[0076] Preparation method: take the above-mentioned traditional Chinese medicine raw materials, add deionized water 10 times the weight of the raw materials, decoct for 4 hours, filter, and use the filtrate A for later use, add deionized water 8 times the weight of the raw materials to the residue, decoct for 4 hours, filter, and filter the filtrate with The filtrates A are combined, concentrated, and dried to obtain extracts that are prepared into pharmaceutical preparations.

Embodiment 2

[0078] Ganoderma lucidum 4000g, Scrophulariaceae 2000g, Salvia miltiorrhiza 2000g, Coptidis 1200g, Fritillaria 1200g, raw oyster 1200g, angelica 1200g, frankincense 800g, myrrh 800g.

[0079] Preparation method: take the above-mentioned traditional Chinese medicine raw materials, add deionized water 10 times the weight of the raw materials, decoct for 4 hours, filter, and use the filtrate A for later use, add deionized water 8 times the weight of the raw materials to the residue, decoct for 4 hours, filter, and filter the filtrate with The filtrates A are combined, concentrated, and dried to obtain extracts that are prepared into pharmaceutical preparations.

Embodiment 3

[0081] Ganoderma lucidum 3000g, Scrophulariaceae 1500g, Salvia miltiorrhiza 1500g, Coptidis 800g, Fritillaria 800g, raw oyster 800g, angelica 800g, frankincense 600g, myrrh 600g.

[0082] Preparation method: take the above-mentioned traditional Chinese medicine raw materials, add deionized water 10 times the weight of the raw materials, decoct for 4 hours, filter, and use the filtrate A for later use, add deionized water 8 times the weight of the raw materials to the residue, decoct for 4 hours, filter, and filter the filtrate with The filtrates A are combined, concentrated, and dried to obtain extracts that are prepared into pharmaceutical preparations.

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Abstract

The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition as well as an application and a preparation thereof. The traditional Chinese medicine composition contains lucid ganoderma, radix scrophulariae, salvia miltiorrhiza, coptis chinensis, thunberg fritillary bulb, raw oyster shell, angelica sinensis, prepared frankincense and prepared myrrh; clinical observation research finds that the prescription can averagely reduce the thickness of the transecting plaque of the carotid atherosclerotic plaque by 16.15%; a double-blind random control test shows that by adopting the formula, the transecting plaque thickness of the carotid atherosclerosis plaque can be averagely reduced by 11.48%; animal experiments find that the internal eliminating and vein softening decoction can activate UCP1, induce adipose tissue activation, promote whole body metabolism and significantly inhibit atherosclerotic plaques in a dose-dependent manner; and no obvious toxic or side effect is found.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition and its use and preparation. The traditional Chinese medicine composition is mainly used for preventing and treating atherosclerotic plaque, especially for preventing and treating "pulse-producing phlegm nucleus" resulting in atherosclerotic plaques. Background technique [0002] There is no concept of atherosclerosis (AS) in TCM literature. According to the etiology, clinical manifestations, complications and other characteristics, it is scattered in TCM "partial dryness", "chest obstruction", "stroke", "vertigo", "headache", "phlegm syndrome", "pain syndrome" Syndrome" and other diseases in the records. Modern Chinese medicine treats AS mostly from blood stasis, phlegm, poison, and deficiency, but the curative effect is not satisfactory. Throughout the history of TCM development, theoretical innovatio...

Claims

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Application Information

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IPC IPC(8): A61K36/8966A61P9/10A61K35/618
CPCA61K36/074A61K36/808A61K36/537A61K36/718A61K36/8966A61K35/618A61K36/232A61K36/324A61K36/328A61P9/10A61K2300/00
Inventor 吴圣贤杜雅薇
Owner DONGZHIMEN HOSPITAL OF BEIJING UNIV OF CHINESE MEDICINE
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