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Skin-whitening, anti-oxidation and soluble cosmetic microneedle mask composition and preparation method thereof

An antioxidant and composition technology, applied in the field of daily chemicals, can solve the problems of inability to reach the dermis layer, slow dissolution of microneedles, unsatisfactory effect, etc., and achieves promotion of cell renewal and even skin tone, soothing and continuous moisturizing, and relieving sun exposure. stimulating effect

Active Publication Date: 2022-01-04
湖北省麦诗特生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] However, soluble microneedles need water to dissolve when used. Too much water will make the soluble microneedles dissolve on the skin surface before entering the skin, and cannot reach the dermis; too little water will make the microneedles dissolve slowly, and the application will consume Long time and unsatisfactory effect

Method used

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  • Skin-whitening, anti-oxidation and soluble cosmetic microneedle mask composition and preparation method thereof
  • Skin-whitening, anti-oxidation and soluble cosmetic microneedle mask composition and preparation method thereof
  • Skin-whitening, anti-oxidation and soluble cosmetic microneedle mask composition and preparation method thereof

Examples

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preparation example Construction

[0060] The preparation method of the jasmine leaf cell extract is as follows: crush the jasmine plant leaves, add 80% ethanol with a mass fraction 13 times the weight of the coarse powder, place in a vacuum environment, and conduct ultrasonic extraction at 65°C.

[0061] Centella Asiatica extract, Polygonum cuspidatum root extract, Scutellaria baicalensis root extract, tea leaf extract, Glycyrrhiza glabra root extract, Chamomile flower extract and Rosemary leaf extract were purchased from Beijing Technology and Business University or Kaye Biotechnology Co., Ltd. company.

Embodiment 1

[0063] A preparation method of skin whitening and anti-oxidation soluble cosmetic microneedle patch composition, comprising the following steps:

[0064] 1) Preparation of viscous liquid:

[0065] Add 0.2% glutathione, 1.5% sodium ascorbyl phosphate, 0.6% nicotinamide, 1% jasmine leaf cell extract to the remaining water, stir to dissolve, then add 10% glycerin, 2% sodium hyaluronate (molecular weight: 5000 Daltons) and 8% sodium hyaluronate (molecular weight is 600,000 Daltons), continue to stir to make it swell evenly, and centrifuge to remove air bubbles to obtain a viscous liquid.

[0066] 2) Preparation of soluble cosmetic microneedles:

[0067] The above-mentioned viscous liquid is injected into a square microneedle mold, dried for 20 hours at room temperature and a humidity of 20%, and the soluble cosmetic microneedle is obtained after demoulding.

[0068] 3) Preparation of hydrogel film:

[0069] Mix 1.5% sodium polyacrylate and 2% aluminum dihydroxyglycinate evenly,...

Embodiment 2

[0073] A preparation method of skin whitening and anti-oxidation soluble cosmetic microneedle patch composition, comprising the following steps:

[0074] 1) Preparation of viscous liquid:

[0075] Add 0.15% glutathione, 1% sodium ascorbyl phosphate, 0.4% nicotinamide, 0.6% jasmine leaf cell extract to the remaining water, stir to dissolve, then add 10% glycerin, 2% sodium hyaluronate (molecular weight: 5000 Daltons) and 8% sodium hyaluronate (molecular weight is 600,000 Daltons), continue to stir to make it swell evenly, and centrifuge to remove air bubbles to obtain a viscous liquid.

[0076] 2) Preparation of soluble cosmetic microneedles:

[0077] With embodiment 1.

[0078] 3) Preparation of hydrogel film:

[0079] With embodiment 1.

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Abstract

The invention discloses a skin-whitening, anti-oxidation and soluble cosmetic microneedle mask composition and a preparation method thereof. The microneedle mask composition comprises a base, a needle body located on the base and a hydrogel mask for relieving and fixing the needle body. A skin-whitening and anti-oxidation composition is embedded in the needle body and comprises 0.05-0.5% of glutathione, 0.2-5% of sodium ascorbyl phosphate, 0.1-2% of nicotinamide and 0.1-5% of a jasmine flower and leaf cell extract. The skin-whitening, anti-oxidation and soluble cosmetic microneedle mask composition can resist oxidation, relieve sun irritation, prevent pigmentation and melanin transmission, promote cell renewal and uniform skin color and achieve a stable skin-whitening effect through a multi-path synergistic effect. The skin-whitening and anti-oxidation composition is embedded in the hyaluronic acid soluble microneedle body, such that the composition can directly reach deep skin, improves percutaneous absorption efficiency, meanwhile, relieves and continuously moisturizes the skin, and further improves the skin-whitening and anti-oxidation effects.

Description

technical field [0001] The invention relates to a skin care product and a preparation method thereof, belonging to the technical field of daily chemicals, in particular to a skin whitening and anti-oxidation soluble cosmetic microneedle patch composition and a preparation method thereof. Background technique [0002] In modern times, it is often said that "one white covers all ugliness", which shows that people's pursuit of beauty is inseparable from fair skin. Melanin is the most important factor in determining the skin color of the human body. Melanin is produced by pigment cells sparsely scattered among the basal cells in the form of tiny particles, and then transferred to the basal cells, and brought to the whole layer of the epidermis as the epidermal cells migrate, while ultraviolet radiation, environmental pollution, endocrine disorders, Genetics and other factors will lead to abnormal metabolism of melanocytes, resulting in increased melanin, local darkening of the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/64A61K8/67A61K8/99A61K8/9789A61K8/73A61K8/34A61K8/02A61Q19/02A61Q19/00A61Q17/04A61M37/00
CPCA61K8/64A61K8/676A61K8/675A61K8/99A61K8/9789A61K8/735A61K8/345A61K8/0208A61Q19/02A61Q19/00A61Q17/04A61M37/0015A61K2800/522A61K2800/592A61K2800/5922A61M2037/0046A61M2037/0053
Inventor 王蕾张金龙何珂周正郭苗
Owner 湖北省麦诗特生物科技有限公司
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