Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Application of dimethyl itaconate in preparation of medicine for preventing and/or treating obesity-induced intestinal micro ecological disorder

A technology of dimethyl itaconate and intestinal microecology is applied in the directions of drug combination, anti-infective drugs, pharmaceutical formulations, etc., to achieve the effect of maintaining integrity, reducing intestinal inflammation, and preventing intestinal microecological disorders.

Pending Publication Date: 2022-02-11
XUZHOU MEDICAL UNIV
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no report on the use of dimethyl itaconate for the prevention and / or treatment of obesity-induced intestinal dysbiosis

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of dimethyl itaconate in preparation of medicine for preventing and/or treating obesity-induced intestinal micro ecological disorder
  • Application of dimethyl itaconate in preparation of medicine for preventing and/or treating obesity-induced intestinal micro ecological disorder
  • Application of dimethyl itaconate in preparation of medicine for preventing and/or treating obesity-induced intestinal micro ecological disorder

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0036] Examples are further listed below to describe the present invention in detail. It should also be understood that the following examples are only used to further illustrate the present invention, and should not be construed as limiting the protection scope of the present invention. Some non-essential improvements and adjustments made by those skilled in the art according to the principles set forth in the present invention all belong to the present invention scope of protection. The specific process parameters and the like in the following examples are only examples of the appropriate range, that is, those skilled in the art can make a selection within the appropriate range through the description herein, and are not limited to the specific data exemplified below.

[0037] The test materials and methods used in the embodiments of the present invention are as follows:

[0038] It should be noted that the following experimental results refer to the corresponding drawings:...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to an application of dimethyl itaconate in the preparation of a medicine for treating and / or preventing obesity-induced intestinal micro ecological disorder. Experiments prove that dimethyl itaconate can correct intestinal micro ecological imbalance of obese mice, reduce intestinal inflammation and maintain intestinal barrier integrity.

Description

technical field [0001] The invention relates to the application of dimethyl itaconate in the preparation of medicines for treating and / or preventing obesity-induced intestinal microecological disorders. Background technique [0002] Obesity is an epidemic and systemic metabolic disease that seriously endangers human health. The Lancet reported in 2016 that there are currently about 600 million obese people in the world. A large amount of evidence shows that obesity can not only significantly increase the risk of heart disease, cerebrovascular disease, diabetes, non-alcoholic fatty liver, hypertension, cancer and other diseases, Moreover, it can cause the decline of cognitive function, which is an important cause of cognitive dysfunction and Alzheimer's disease. Therefore, related diseases caused by obesity have become serious public health problems. [0003] Intestinal microecological balance is an important factor in maintaining human health. Long-term intake of high-fat...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K31/225A61P3/04A61P1/00A61P31/00
CPCA61K31/225A61P3/04A61P1/00A61P31/00
Inventor 于英华潘伟徐大祥杨晓莹吴佳诚赵进秀张鹏胡敏敏胡涛李梦迪
Owner XUZHOU MEDICAL UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com