Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

2, 5-thiophene-diformaldehyde-2-amino-4-methylphenol Schiff base and preparation method and application thereof

A technology of methyl phenol and diformaldehyde, applied in 2 fields, can solve the problem of less synthesis of bis-Schiff bases, etc.

Pending Publication Date: 2022-02-25
福州市第二医院
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the Schiff bases reported in the literature are mainly single Schiff bases, and the synthesis of aromatic ring bis-Schiff bases is relatively rare.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • 2, 5-thiophene-diformaldehyde-2-amino-4-methylphenol Schiff base and preparation method and application thereof
  • 2, 5-thiophene-diformaldehyde-2-amino-4-methylphenol Schiff base and preparation method and application thereof
  • 2, 5-thiophene-diformaldehyde-2-amino-4-methylphenol Schiff base and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 12

[0025] Example 1 The preparation method of 2,5-thiophene-dimethylaldehyde acetal 2-amino-4-methylphenol Schiff base compound:

[0026] Weigh 0.140g of 2,5-thiophene-diformaldehyde and dissolve it in 20.0mL of absolute ethanol to obtain a 2,5-thiophene-diformaldehyde solution, weigh 0.246g of 2-amino-4-methylphenol and dissolve it in 20.0mL Prepare 2-amino-4-methylphenol solution with absolute ethanol, add 2-amino-4-methylphenol solution dropwise to 2,5-thiophene-diformaldehyde solution and react at 50°C for 2 hours to form crystals , filtered with suction, washed with ethanol, and dried naturally to obtain crystals, then washed with 50.0 mL of absolute ethanol, and dried at 50° C. for 1 h to obtain orange-yellow crystals.

[0027] The crystal is 2,5-thiophene-dimethylaldehyde acetal 2-amino-4-methylphenol Schiff base, which is composed of one molecule of 2,5-thiophene-dimethylaldehyde and two molecules of 2-amino-4- Schiff base formed by condensation of methylphenol.

[0028...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a 2, 5-thiophene-diformaldehyde-2-amino-4-methylphenol Schiff base and a preparation method and application thereof, and belongs to the technical field of organic synthesis. The Schiff base is prepared by taking 2, 5-thiophene-dicarboxaldehyde and 2-amino-4-methylphenol as raw materials, reacting at 45-55 DEG C according to a molar ratio of 1: 2 in the presence of an organic solvent, and after the reaction is finished, separating, washing and drying. The 2, 5-thiophene-diformaldehyde-2-amino-4-methylphenol Schiff base compound is a Schiff base with a novel structure, is simple in preparation method and can be used for detecting copper ions.

Description

technical field [0001] The invention relates to the technical field of organic synthesis, in particular to a 2,5-thiophene-dimethylaldehyde acetal 2-amino-4-methylphenol Schiff base and its preparation method and application. Background technique [0002] Schiff's base mainly refers to a class of organic compounds containing imine or imine groups, usually formed by the condensation of compounds containing active carbonyl groups and primary amines. In recent years, Schiff bases have a wide range of biological and pharmaceutical activities such as antibacterial, anticancer, antioxidative, and antiviral properties, as well as enzymatic catalysis, photoelectric properties, and fluorescent properties, so they have attracted more and more attention from researchers. At present, the Schiff bases reported in the literature are mainly mono-Schiff bases, and the synthesis of aromatic ring bis-Schiff bases is relatively rare. [0003] The two aldehyde groups in 2,5-thiophene-dimethylf...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C07D333/22C09K11/06G01N21/64
CPCC07D333/22C09K11/06G01N21/643C09K2211/1007C09K2211/1092
Inventor 何文慧吴冬枝韩志钟张怡元张韬郑茂镇
Owner 福州市第二医院
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com