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Bifidus yeast freeze-dried powder composition and preparation method thereof

A technology of bifid yeast and freeze-dried powder, which is applied in the field of bifid yeast freeze-dried powder composition and its preparation, can solve the problems of insignificant skin repair effect, achieve improved skin penetration effect, high repair efficiency, and promote skin metabolism Effect

Pending Publication Date: 2022-04-26
安婕妤化妆品科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In cosmetics, lyophilized powder is usually used together with a solvent (such as water), but in such cosmetic preparations with lyophilized powder and solvent, most of the active ingredients exist in the lyophilized powder, and the optimization of the solvent formula is ignored, resulting in The skin repair effect is not significant, it must be used with other essence or emulsion products to promote the skin to absorb the active ingredients in the freeze-dried powder

Method used

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  • Bifidus yeast freeze-dried powder composition and preparation method thereof
  • Bifidus yeast freeze-dried powder composition and preparation method thereof

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preparation example Construction

[0035] In a second aspect, the present invention provides a method for preparing the bifid yeast freeze-dried powder composition as described in the first aspect, comprising the steps of:

[0036] (1) Mix the filtrate of the fermented product of bifida yeast, oligopeptide-1, pH regulator, mannitol and water evenly, then filter and subpackage, then pre-freeze, freeze-dry to obtain a powder;

[0037] (2) Mix the skin conditioning agent, moisturizing agent, chelating agent, antioxidant, excipient and water evenly, filter and fill to obtain the water preparation.

[0038] In one embodiment, the temperature of the pre-freezing treatment is -45 to -40° C., and the time is 5 to 12 hours.

[0039] In one embodiment, the freeze-drying step specifically includes: evacuating at -45 to -40°C, maintaining the vacuum at 1 to 30Pa, and controlling the temperature from -45 to -40°C to -5 to 0°C. ℃, the control temperature gradient is 10~20℃, and the freeze-drying time of each temperature gra...

Embodiment 1

[0044] The preparation method of a kind of bifid yeast freeze-dried powder composition provided by the present embodiment comprises the following steps:

[0045] Weigh the raw materials of the powder by weight percentage: mannitol 7%, disodium hydrogen phosphate 0.72%, sodium dihydrogen phosphate 0.28%, oligopeptide-1 0.1%, bifid yeast fermentation product filtrate 10%, water balance, will Add disodium hydrogen phosphate, sodium dihydrogen phosphate and deionized water into the mixer to mix and dissolve, then add mannitol, oligopeptide-1 and bifid yeast fermentation product filtrate into the mixer, at a speed of 800r / min Stir for 15 minutes, filter with a filter membrane with a pore size of 0.22 μm, transfer the filtrate to a freeze dryer, pre-freeze at -45 to -40°C for 3 hours, and vacuum at -40°C. The vacuum degree is maintained at 10Pa, the control temperature rises from -40°C to 0°C, the control temperature gradient is 10°C, and the freeze-drying time of each temperature g...

Embodiment 2

[0048] Repeat the method of embodiment 1 to make powder;

[0049] Weigh the raw materials of the water preparation by weight percentage: 0.03% disodium edetate, 2% trehalose, 4% glycerin, 4% butanediol, 0.12% sodium hyaluronate, 0.06% sclerotinia, glycyrrhizic acid Dipotassium 0.04%, Niacinamide 1.2%, p-Hydroxyacetophenone 0.4%, 1,2-Hexanediol 0.8%, Caprylyl Glycol 0.1%, Propylene Glycol 2%, False Leaf Root Extract 0.4%, Centella Asiatica Extract 0.6%, escin 0.3%, hydrolyzed yeast protein 0.8%, palmitoyl tripeptide-1 1.5%, palmitoyl tetrapeptide-71.2%, hydroxypropyltetrahydropyrantriol 0.2%, deionized water balance , according to the method for embodiment 1, prepare aqua.

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Abstract

The invention discloses a bifidus yeast freeze-dried powder composition and a preparation method thereof. The bifidus yeast freeze-dried powder composition comprises powder and an aqueous solution, wherein the powder comprises the following raw materials: bifidus yeast fermentation product filtrate, oligopeptide-1, a pH regulator, mannitol and the balance of water; the water aqua comprises the following raw materials: a skin conditioner, a humectant, a chelating agent, an antioxidant, an excipient and the balance of water. The bifidus yeast freeze-dried powder composition provided by the invention comprises the powder and the water aqua, the use effect is prevented from being influenced by mixing and dissolving of powder components and water aqua components through independent packaging of the powder and the water aqua, and when the bifidus yeast freeze-dried powder composition is used, the powder and the water aqua are uniformly mixed and then smeared on the skin, so that the skin is not irritated; test results show that through scientific and reasonable proportioning, the obtained water aqua can promote skin metabolism, improve the skin permeation effect of the active ingredients of the powder and enhance the effects of moisturizing and brightening the skin, and the efficiency of repairing damaged skin is high through the synergistic effect of the water aqua and the active ingredients.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a bifid yeast freeze-dried powder composition and a preparation method thereof. Background technique [0002] Freeze-dried powder is a powder obtained by freezing a liquid into a solid in a low-temperature environment and then drying it, which can avoid the damage of active ingredients by heating to the greatest extent, and was first used in the production of heat-sensitive medicines or biological products. With the continuous development of technology, freeze-dried powder cosmetics have received more and more attention. In cosmetics, lyophilized powder is usually used together with a solvent (such as water), but in such cosmetic preparations with lyophilized powder and solvent, most of the active ingredients exist in the lyophilized powder, and the optimization of the solvent formula is ignored, resulting in The skin repair effect is not significant, and it must be used with ...

Claims

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Application Information

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IPC IPC(8): A61K8/9728A61K8/9789A61K8/64A61K8/34A61K8/73A61K8/63A61K8/67A61K8/65A61Q19/00A61K8/49
CPCA61K8/9728A61K8/64A61K8/345A61K8/735A61K8/63A61K8/675A61K8/9789A61K8/645A61K8/65A61Q19/00A61K8/498A61K2800/84A61K2800/882
Inventor 石毛林志隆李菲
Owner 安婕妤化妆品科技股份有限公司
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