Prosthetic heart valve with sealing frame to reduce perivalvular leakage

Abstract

The invention relates to a prosthetic heart valve with a sealing frame to reduce perivalvular leakage. The sealing frame surrounds a radially outer surface portion of a valve frame of the prosthetic heart valve. Both the valve frame and the sealing frame are radially collapsible and expandable between respective compressed and expanded configurations. The sealing frame has a first axial end coupled to the valve frame at an inflow end thereof and a second axial end coupled to the valve frame at a location between the inflow end and an outflow end thereof. The sealing frame also has an intermediate portion between the first axial end and the second axial end that projects radially outward when the valve frame and the sealing frame are in their expanded configuration. The sealing frame displaces the outer skirt of the prosthetic heart valve radially outward and urges the outer skirt into contact with surrounding autologous tissue, thereby reducing or avoiding perivalvular leakage. In some examples, the sealing frame may be formed from a shape memory material.

Description

[0001] CROSS-REFERENCE TO RELATED APPLICATIONS [0002] This application claims the benefit of U.S. Provisional Application No. 63 / 112,567, filed November 11, 2020, which is incorporated herein by reference. technical field [0003] The present disclosure relates to prosthetic heart valves, particularly prosthetic heart valves having sealing frames to reduce paravalvular leakage. Background technique [0004] The human heart can suffer from a variety of valve diseases, which can lead to severe dysfunction of the heart and ultimately require repair of the native valve or replacement of the native valve with an artificial valve. There are many known prosthetic devices (e.g., annuloplasty rings) and prosthetic valves, as well as many known methods of implanting these devices and valves into the human body. Percutaneous and minimally invasive surgical methods are used in a variety of procedures to deliver artificial medical devices to locations within the body that are not easi...

AI Technical Summary

Problems solved by technology

However, since this outer skirt lacks any type of inner support, some anatomical features may limit the effectiveness in preventing PVL

For example, when the portion of the patient's anatomy into which the valve is implanted is relatively rigid (e.g., due to calcified nodules) and / or when the shape of the anatomy exceeds the dimensions of the implanted valve frame (e.g., due to the relatively thin caused by large commissural gaps), the outer skirt may not be able to close the gap between the exterior of the valve frame and the surrounding autologous tissue

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