Composition for preventing and treating female physiological cycle disorder caused by plateau hypoxia and application

Abstract

The invention discloses a composition for preventing and treating female physiological cycle disorder caused by plateau hypoxia and application. The composition is prepared from, by mass, 24 parts of radix astragali extract, 16 parts of poria cocos extract, 18 parts of caulis polygoni multiflori extract, 21 parts of radix codonopsis extract, 8 parts of radix angelicae sinensis extract, 11 parts of radix salviae miltiorrhizae extract and 2 parts of 5-hydroxytryptophan. Experiments prove that the composition disclosed by the invention can remarkably prolong the normal-pressure closed hypoxia survival time of female mice and can remarkably improve female physiological cycle disorder caused by plateau hypoxia exposure.

Description

technical field [0001] The invention belongs to the field of biotechnology, and in particular relates to a composition for preventing and treating female physiological cycle disorder caused by high altitude hypoxia. Background technique [0002] At present, there are more than 500 million people living in the plateau and alpine areas in the world, and my country's plateau area is vast, and the area above 3,000m above sea level accounts for about 1 / 6 of the country's total area. The country with the largest population living in the highlands and high mountains. The plateau is a special environment with many unfavorable factors for the human body, such as low air pressure, low partial pressure of oxygen, cold, dryness and strong sunlight radiation, etc. Among them, low oxygen is the biggest threat, and the partial pressure of oxygen inhaled in the plateau at an altitude of 4600 meters is almost Only half of the sea level area, the unique natural environment factors of the plat...

AI Technical Summary

Problems solved by technology

However, whether anti-hypoxia can improve the menstrual cycle disorder of high-altitude hypoxic females has not been reported yet.

5-hydroxytryptophan was first discovered in serum, also known as serotonin, 5-hydroxytryptophan is the precursor of serotonin, in animal and human experiments, 5-hydroxytryptophan can promote the metabolism of catecholamines, especially It has a promoting effect on dopamine and norepinephrine. Studies have shown that 5-hydroxytryptophan has the effect of regulating mood and sleep. In addition, previous experimental studies have found that the physiological cycle of female rats exposed to plateau hypoxia is disturbed by luteinizing hormone. Abnormal secretion, whether 5-hydroxytryptophan can improve the menstrual cycle disorder of high-altitude hypoxic females has not been reported yet

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