Application of rhaponticum aestivum alcohol extract in treatment and/or prevention of diabetes mellitus

Abstract

The invention discloses application of a rhaponticum aestivum alcohol extract in treatment and / or prevention of diabetes mellitus. The rhaponticum aestivum alcohol extract can reduce fasting blood-glucose of diabetic mice, regulate blood fat indexes such as total cholesterol and total triglyceride and sugar tolerance of the diabetic mice, improve the tissue morphology of pancreas, liver, kidney and blood vessels of the diabetic mice and improve liver, kidney and blood vessel injuries of the diabetic mice. Therefore, the rhaponticum aestivum has huge potential for treating diabetes mellitus and has great clinical application value, the rhaponticum aestivum plays a role in regulating the whole body and improving comprehensive symptoms, and the main way of reducing blood sugar is to improve insulin resistance, protect liver and kidney functions, improve vasculopathy and other factors, so that the rhaponticum aestivum can be used for treating diabetes mellitus. And the occurrence of complications is reduced or reduced through integral regulation and comprehensive intervention.

Description

technical field [0001] The invention belongs to the technical field of natural product chemistry, and in particular relates to the application of an alcohol extract of cerevisiae in the treatment and / or prevention of diabetes. Background technique [0002] Diabetes is the third most common chronic disease in the world, and its incidence is second only to tumors and cardiovascular diseases, which seriously threatens human health and life. The pathological development process of diabetes is very complicated. With the prolongation of the onset time, it can also lead to various complications such as the eyes, kidneys, nerves and cardiovascular of the patient, resulting in chronic multi-system diseases and loss of function in the body, which is the cause of high mortality and high mortality. main cause of disability. After the occurrence of insulin resistance in the process of diabetes, the effect of insulin on inhibiting lipolysis is significantly weakened, which promotes the r...

AI Technical Summary

Problems solved by technology

Although the active components in deer grass such as quercetin have been found to reduce blood sugar levels in diabetic mice, the reported pharmacological activity of a single active component does not reflect the regulatory effect of deer grass on blood sugar and blood lipids in diabetes, nor can it elucidate The systemic and holistic compatibility characteristics of various active ingredients in deer grass to play a synergistic effect

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