Dietary fiber composition with effects of reducing blood glucose and lipid and losing weight

A dietary fiber, hypoglycemic and lipid-lowering technology, which is applied in the direction of medical preparations containing active ingredients, drug combinations, food science, etc., can solve the problem of unreasonable dietary fiber dosage and combination, decreased physical strength, resistance, and weight and body fat rebound To achieve the effect of reducing the total cholesterol content of the liver, reducing fasting blood sugar, and improving fatty liver

Pending Publication Date: 2019-08-09
汉济生物科技(武汉)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are a large number of reports about dietary fiber compositions on the market at present, but most of them only focus on the function of reducing fat and reducing fat, and ignore the absorption structure that dietary fiber itself should match human nutrients, thereby causing the following defects: (1) the consumption of dietary fiber And the combination is unreasonable. After stopping eating, due to the compensatory effect of the body, it is very easy to rebound in physiological indicators such as body weight and body fat; If the intake of elements is affected, there will be a decrease in physical strength and resistance, and even cause malnutrition and other diseases

Method used

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  • Dietary fiber composition with effects of reducing blood glucose and lipid and losing weight
  • Dietary fiber composition with effects of reducing blood glucose and lipid and losing weight
  • Dietary fiber composition with effects of reducing blood glucose and lipid and losing weight

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Divide highland barley powder, inulin, konjac powder and chia seed powder into three types of dietary fiber: β-glucan rich in highland barley powder is a type of dietary fiber that can be slowly absorbed by the human body (hereinafter referred to as type 1 dietary fiber fiber), inulin and konjac flour are a type of dietary fiber that can be fermented and utilized by intestinal flora (hereinafter referred to as Type 2 dietary fiber), and the dietary fiber provided by chia seeds is dietary fiber that can completely resist digestion and utilization (hereinafter referred to as known as Type 3 dietary fiber). According to this classification method, eight groups of dietary fiber compositions with different ratios were designed, as described in Table 1 for details.

[0019] Table 1 Tested dietary fiber composition ratio (g)

[0020]

[0021] All the materials are crushed and passed through a 60-100 mesh sieve; after mixing evenly, ultraviolet sterilization is carried out....

Embodiment 2

[0035] 110 male 6-week-old Kunming mice were selected, 10 were normal controls, fed with normal diet, and 100 were fed with high-fat and high-sugar diet. Seven days later, 2% streptozotocin (STZ) was injected intraperitoneally at 0.1 g / kg body weight, and the diet was resumed 1 hour after the injection to establish a type 2 diabetes model (this method is a commonly used diabetic mouse model). After the modeling was completed, the fasting blood glucose after fasting for 5 hours was measured, and the mice whose fasting blood glucose value was higher than 16.7mol / L were selected for the experiment. A total of 90 mice met the requirements, and 90 mice that were successfully modeled plus 10 mice were selected. The mice in the normal control group were divided into groups according to the following method:

[0036] Dietary fiber composition feeding group: a total of 8 groups of dietary fiber composition in Table 1, 10 of each composition, a total of 80;

[0037] Model control group...

Embodiment 3

[0058] The present embodiment investigates the influence of the dietary fiber composition of the present invention on human body mass index (BMI) through the human body experiment, and then reflects the dietary fiber composition on volunteers' hyperlipidemia, hyperglycemia, hypertension, high uric acid and fat Whether the decline of liver and other indicators has a certain effect.

[0059] Select 40 cases of obesity (BMI>28) (20 cases for each male and female), aged 30-55 years old, these volunteers are based on their own age, height, weight, daily activity, according to the "Dietary Guidelines for Chinese Residents 2016" The calorie calculation formula in the design recommends recipes, and the calorie range is 2100-2700kcal / d. The recipe is designed to take a pack (20g) of dietary fiber composition (composition 3 in Table 1: barley powder 70%, inulin 13%, konjac powder 9%, chia seed powder 8%) every night in the recipe, and add it to the total recipe Deduct the corresponding...

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Abstract

The invention discloses a dietary fiber composition. The dietary fiber composition is prepared from, by weight, 30-83% of highland barley powder, 10-30% of inulin, 5-20% of konjaku flour and 2-20% ofchia seed powder. Animal test results show that the dietary fiber composition has the effects of losing weight and reducing blood glucose and lipid, and cannot cause excessive weight loss or weaknessof mice after being eaten. Human feeding trial results show that the dietary fiber composition can significantly reduce the BMI index of obesity groups, half a year after the dietary fiber compositionstops being eaten, the BMI index does not rebound, and therefore the dietary fiber composition has a better healthcare effect.

Description

technical field [0001] The invention belongs to the field of health food, and in particular relates to a dietary fiber composition with functions of lowering blood sugar, lowering fat and reducing weight. Background technique [0002] With the continuous improvement of residents' living standards, the incidence of metabolic diseases such as hypertension, hyperglycemia (diabetes), hyperlipidemia, and hyperuric acid is increasing. Metabolic diseases are mostly related to overnutrition. Scientific research shows that obesity caused by overnutrition is directly related to the symptoms of "four highs". Therefore, controlling or reducing excessive nutrient absorption is gradually regarded as an important health care method. The low-calorie, high-satiety meal replacement diet is a dietary pattern that controls excessive nutrient intake. Among them, dietary fiber can provide high satiety while having low calories, and can also play a role in intestinal probiotics. Beneficial effec...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/22A61K36/899A61P3/10A61P3/06A61P1/16A61P9/12A61P19/06A61P3/04A61K31/733
CPCA23L33/22A61K36/899A61K31/733A61K36/888A61K36/537A61P3/10A61P3/06A61P1/16A61P9/12A61P19/06A61P3/04A23V2002/00A23V2200/3202A23V2200/3324A23V2200/328A23V2200/326A23V2200/30A61K2300/00
Inventor 李超英
Owner 汉济生物科技(武汉)有限公司
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