Low-frequency focusing electrical stimulation device and method

Abstract

The embodiment of the invention discloses a low-frequency focusing electrical stimulation device and method, and the device comprises an ultrasonic wave transmitting module which is used for transmitting three ultrasonic waves to a target position, the three ultrasonic waves are perpendicular in pairs and are focused at the target position of a to-be-stimulated sample, and the center frequencies of the three ultrasonic waves form an arithmetic progression; a signal frequency difference value of two ultrasonic beams with adjacent frequencies is equal to a preset interference frequency; the static magnetic field generation module is used for generating a constant and stable static magnetic field at a target position, so that the constant and stable static magnetic field and the three beams of ultrasonic waves generate target low-frequency alternating-current electric signals at the target position, and the magnetic field direction of the constant and stable static magnetic field is perpendicular to the combined direction of the three beams of ultrasonic waves emitted by the ultrasonic wave emission module. According to the technical scheme of the embodiment of the invention, the effect of providing a low-frequency induction electric field and current which are spatially symmetrical and high in resolution ratio to induce electrical activity of neurons is achieved.

Description

technical field [0001] Embodiments of the present invention relate to electrical stimulation technology, and in particular, to a low-frequency focused electrical stimulation device and method. Background technique [0002] Existing magneto-acoustic coupling stimulation devices mainly use a single ultrasonic transducer to inject high-frequency (MHz-level) ultrasonic waves into the conductive tissue to be stimulated, and at the same time apply a static magnetic field perpendicular to the propagation direction of the ultrasonic waves. Here, a high-frequency (MHz-level) induced electric field and current with a frequency equivalent to the ultrasonic frequency are generated, which is suitable for studying the effect of high-frequency (MHz-level) electrical stimulation on neurons. [0003] However, neurons have low-pass filtering properties, so the magneto-acoustic coupled stimulation generated by the existing magneto-acoustic coupled stimulation devices cannot generate low-freque...

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Problems solved by technology

[0003] However, neurons have low-pass filtering characteristics, so the magneto-acoustic coupling stimulation produced by the existing magneto-acoustic coupling stimulation device cannot generate low-frequency currents that are more likely to trigger neuron responses

Moreover, the use of a single ultrasonic transducer will cause the focus of the ultrasonic beam to be well focused only in the direction perpendicular to the propagation direction, and poorly focused in other directions

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