Unlock instant, AI-driven research and patent intelligence for your innovation.

Ultrasonic pipetting method and system based on annular array ultrasonic transducer

An ultrasonic transducer and annular array technology, applied in the field of ultrasonic pipetting methods and systems thereof, can solve the problems of high cost, complex structure, difficult pipetting, etc., and achieve the effects of low cost, simple operation and low equipment cost.

Pending Publication Date: 2022-07-22
SHENZHEN INSIGHTSONICS CO LTD
View PDF9 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This scheme uses a large number of micromachined ultrasonic transducers to form an array ultrasonic transducer, which is not only expensive, but also has an extremely complex structure, making it difficult to accurately operate the array ultrasonic transducer to achieve liquid transfer.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Ultrasonic pipetting method and system based on annular array ultrasonic transducer
  • Ultrasonic pipetting method and system based on annular array ultrasonic transducer
  • Ultrasonic pipetting method and system based on annular array ultrasonic transducer

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] This embodiment proposes an ultrasonic pipetting method based on a ring array ultrasonic transducer, which can realize liquid parameter detection and non-contact ultrasonic pipetting. It not only has the characteristics of safety and accuracy of non-contact pipetting, but also has system complexity Low cost, low equipment cost and simple operation. The flow chart of ultrasonic pipetting method based on annular array ultrasonic transducer is attached figure 1 As shown, the specific scheme is as follows:

[0056] An ultrasonic pipetting method based on an annular array ultrasonic transducer includes multiple measurement operations and at least one pipetting operation. Multiple measurement operations can accurately obtain liquid parameters, and then adjust appropriate parameters for pipetting operations. The number of pipetting operations can be set according to the actual application.

[0057] Each measurement operation includes:

[0058] 101. Excite the central array e...

Embodiment 2

[0087] This embodiment provides an ultrasonic pipetting system based on an annular array ultrasonic transducer, which systematizes the method of Embodiment 1. The schematic structural diagram of the system is shown in the appendix of the description. Image 6 As shown, the specific scheme is as follows:

[0088] An ultrasonic pipetting system based on an annular array ultrasonic transducer 2, comprising,

[0089] The control unit 1 is connected to the annular array ultrasonic transducer 2 for exciting the annular array ultrasonic transducer 2 to emit ultrasonic signals. By exciting the annular array ultrasonic transducer 2 to emit different ultrasonic signals, the ultrasonic pipetting system can be controlled to switch between the pipetting mode and the measurement mode.

[0090] The annular array ultrasonic transducer 2 includes a circular array element and at least one annular array element; it is used to perform part of the measurement operation and part of the pipetting o...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides an ultrasonic pipetting method and system based on an annular array ultrasonic transducer. The method comprises measurement operation and pipetting operation. The measurement operation comprises the following steps: exciting the array element to generate emission ultrasonic waves in a short pulse form, and generating reflection ultrasonic waves after reaching the liquid level; and each array element receives the reflected ultrasonic waves and performs dynamic beam forming to obtain and analyze ultrasonic beams to obtain liquid parameters. The pipetting operation comprises the following steps: adjusting excitation parameters according to liquid parameters; and the central array element and at least one non-central array element are excited to generate emission ultrasonic waves in a long pulse form, the emission ultrasonic waves are focused on the liquid level, and the solution in the source liquid carrying platform is moved to a preset target liquid carrying platform in a liquid drop form. According to the scheme, liquid parameter detection and non-contact type ultrasonic pipetting are achieved based on the annular array ultrasonic transducer, the non-contact type ultrasonic pipetting device has the advantages of being safe and accurate in non-contact type pipetting, the system complexity is low, the equipment cost is low, and operation is easy.

Description

technical field [0001] The invention relates to the field of ultrasonic applications, in particular, to an ultrasonic pipetting method and system based on an annular array ultrasonic transducer. Background technique [0002] Synthetic biology is hailed as one of the world's three most disruptive technologies to meet the challenge. Pipetting is one of the most common tasks in a synthetic biology laboratory, and choosing the right pipette is a critical step in completing an experiment accurately. According to whether the liquid is in contact with the solution during the pipetting process, the pipetting methods can be divided into contact pipetting and non-contact pipetting. [0003] Contact pipetting, such as a pipette. During the pipetting process, the sample will stick to the pipette tip, making the amount of liquid transferred inaccurate and possibly producing huge false negative results. And errors can accumulate with serial dilutions, with some samples showing up to a ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/02
CPCB01L3/0241B01L2400/0439
Inventor 宋爽
Owner SHENZHEN INSIGHTSONICS CO LTD