Health food composition for liver
A composition and health technology, applied in food science, food preparation, medical preparations containing active ingredients, etc., can solve problems such as unclear pharmacological mechanism
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Embodiment 1
[0047] Healthy food composition for the liver
[0048] Compositions of liver health foods were prepared from the following components:
[0049] Artemisia saponica var.
[0050] In the following animal tests, the promotion of liver function of the composition was tested:
Embodiment 1
[0051] Experimental Example 1: Effect of Health Food on Acute Insufficiency
[0052] Sprague-Dawley rats weighing approximately 200 grams were incubated in an animal testing room maintained at constant temperature and humidity for 1 week or longer prior to testing. Rats deemed healthy were selected for testing.
[0053] The selected 50 rats were divided into 5 groups, 10 rats in each group, and then administered. For the test group, the composition suspended in 9% saline was intravenously injected at 1 mg / kg / day, 20 mg / kg / day and 100 mg / kg / day for 4 days. After the evening of the last day of injection, the test group was orally administered carbon tetrachloride (CCl) in a ratio of 1:4 (v / v) at a dose of 0.2 ml per kg body weight. 4 ) and corn oil. For both control groups, only 0.9% saline was used during the injection period. After the evening of the last day of injection, one of the control groups was fed corn oil and the other was orally administered a mixture of carbon ...
Embodiment 2
[0068] Comparison of composition and alpha-tocopherol in promoting liver function
[0069] Alpha-tocopherol, known to promote liver function, was compared with the composition of the present invention. For this, the composition of the present invention and α-tocopherol were administered to rats in the same manner as in Example 1 at 20 mg / kg / day and 350 mg / kg / day, respectively. The S-AST and S-ALT activities of blood samples obtained from each test group were measured. The results are given in Table 3 below.
[0070] table 3
[0071] Group
S-AST
S-ALT
Value (U / L)
ratio
Value (U / L)
ratio
control
100±4
4.1
38±1
2.6
Control administered with CCl4
2439±148
100.0
1482±44
100.0
Apply the composition
1251±117
50.9
276±19
18.6
[0072] As seen in Table 3, compared with α-tocopherol, when the health food composition...
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