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Medicinal composition for treating coronary heart disease and angina pectoris

A technology of coronary heart disease angina pectoris and composition, which is applied in the field of drugs for preventing and treating coronary heart disease angina pectoris, and can solve the problems of low curative effect and unsatisfactory effect of promoting blood circulation and removing blood stasis of Shenshao Tablets, etc.

Inactive Publication Date: 2006-02-22
邢亚东
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the curative effect of Shenshao Tablets is still low, and the effect of promoting blood circulation and removing blood stasis is not satisfactory.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Example 1 Preparation of Capsules

[0020] Weigh 1750 grams of Radix Paeoniae Rubra, 13 grams of total saponins from ginseng stems and leaves, and 210 grams of turmeric.

[0021] Soak the Radix Paeoniae Rubra in water for 2 hours and then decoct twice, 1 hour each time. The filtrates were combined, concentrated to a relative density of 1.05-1.10 (measured at 50°C), and impurities in the water extract were removed by precipitation with 70% ethanol, and the ethanol was recovered under reduced pressure. Vacuum-dried into a dry extract, crushed, sieved, added ginseng stem and leaf total saponins and turmeric powder, mixed evenly, dried (below 60°C), and packed into 1000 capsules. Generally, adults take 4 capsules orally each time, 2 times a day.

Embodiment 2

[0022] Embodiment 2 preparation tablet

[0023] Weigh 3500 grams of Radix Paeoniae Rubra, 60 grams of total saponins from ginseng stems and leaves, and 500 grams of turmeric.

[0024] Soak the Radix Paeoniae Rubra in water for 3 hours and then decoct twice, 1 hour each time. The filtrates were combined, concentrated to a relative density of 1.05-1.10 (measured at 50°C), and impurities in the water extract were removed by precipitation with 70% ethanol, and the ethanol was recovered under reduced pressure. Vacuum dried into a dry extract, crushed, sieved, added ginseng stem and leaf total saponins and turmeric powder, mixed evenly, dried (below 60°C), and compressed into 4000 tablets. Generally, adults take 4 tablets orally each time, 3 to 4 times a day.

Embodiment 3

[0025] Example 3 Curative Effect Observation on Treating 108 Cases of Coronary Heart Disease Angina Pectoris

[0026] (1) Case selection criteria and test methods

[0027] According to the diagnostic criteria of coronary heart disease and referring to the "nomenclature and diagnostic criteria of ischemic heart disease" formulated by WHO, 200 inpatients and outpatients with coronary heart disease and angina pectoris were randomly divided into treatment group and control group. Among the 108 patients in the treatment group, there were 68 males and 40 females; the age ranged from 38 to 77 years, with an average age of 57 and 66 years. Of the 92 cases in the control group, there were 55 males and 37 females, with an average age of 56 and 44 years. There was no significant difference in age and gender between the two groups.

[0028] The control group took Nitongding Tablets 10mg orally, 3 times a day. The treatment group took orally the capsules made according to the method of ...

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Abstract

The medicine composition for treating coronary heart disease and angina pectoris is prepared with ginseng stem and leaf total saponin, red peony root and curcuma root. Its red peony root component is extracted via water decoction and alcohol deposition. The medicine composition may be prepared into capsule, tablet, granule, oral liquid or other preparation form. It is suitable for treating coronary heart disease with insufficient blood supply, miocardial infarction, arrhythmia, cardiac functional insufficiency, etc.

Description

(1) Technical field [0001] The invention relates to a medicine for preventing and treating angina pectoris of coronary heart disease, especially a medicine preparation prepared with Chinese medicinal materials. (2) Background technology [0002] Coronary heart disease and angina pectoris are common and frequently-occurring diseases that seriously endanger the health of middle-aged and elderly people. Most of the medicines for internal medicine of this disease in modern medicine focus on relieving the acute symptoms of angina pectoris, and it is difficult to achieve a lasting and stable curative effect. And these medicines often appear larger side effects when the dosage is increased for the usual dosage or to relieve the symptoms of angina pectoris rapidly. Traditional Chinese medicine has its own characteristics and advantages in the treatment of coronary heart disease angina pectoris, and many Chinese patent medicines have certain curative effects on the treatment of coro...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P9/10A61K9/48A61K9/20
Inventor 胡锦心邢亚东
Owner 邢亚东
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