Aroxyphenoxy carboxylic acid ester compounds with herbicidal activity
A technology for aryloxyphenoxycarboxylic acids and ester compounds, which is applied in the directions of organic chemistry, animal repellents, plant growth regulators, etc., can solve the problems of undisclosed biscarboxyl ester compounds and the like
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[0091] Synthesis of Compound 1 in Table 1:
[0092]
[0093] Add raw material a (30.0 g, 0.092 mol) and 150 ml of dichloromethane into a 250 ml reaction flask, stir, add oxalyl chloride (14.0 g, 0.110 mol), 3 drops of DMF, stir at room temperature for 4 hours, and concentrate to obtain 32 g of yellow liquid b1.
[0094]
[0095] Add ethylene glycol (31.0 grams, 0.50mol) in the reaction flask of 250ml, triethylamine (6.1 grams, 0.06mol), in the 100ml dichloromethane solution, add dropwise b1 (17.3 grams, 0.05mol) and The mixed solution of 50ml of dichloromethane was added in about half an hour and reacted at room temperature for 5 hours. Pour the mixed solution into a 1000ml separating funnel, add 200ml ethyl acetate and 200ml water, and separate the liquids. The ethyl acetate layer is washed with 200ml saturated aqueous sodium bicarbonate solution and 200ml saturated aqueous sodium chloride solution, dried over anhydrous magnesium sulfate, and concentrated , separated ...
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