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Flunarizine hydrochloride injection and its prepn process

A technology of flunarizine hydrochloride and preparation process, applied in the field of western medicine, can solve the problems of low bioavailability, difficult oral administration and slow absorption in critically ill patients, and achieve the effects of pain relief, significant curative effect and rapid action

Inactive Publication Date: 2002-12-11
曹长城
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The existing flunarizine hydrochloride only has oral capsules, which not only has low bioavailability and slow absorption, but also is very difficult for critically ill patients to take orally

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach

[0011] Example formula one: flunarizine hydrochloride 1%, benzyl alcohol solution 0.01%, 1,2-propanediol solution 8%, activated carbon 0.01%.

[0012] Example formula II: Flunarizine hydrochloride 3%, benzyl alcohol solution 0.03%, 1,2-propylene glycol solution 12%, activated carbon 0.05%.

[0013] Example formula three: flunarazine hydrochloride 3%, benzyl alcohol solution 0.01%, 1,2-propanediol solution 15%, activated carbon 0.01%.

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PUM

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Abstract

Flunarizine hydrochloride injection is compounded with Flunarizine hydrochloride, benzoic alcohol solution, propylene glycol solution, active carbon and water for injection in certain proprtion. It is used for salving critical patient and has quick and obvious curative effect. It can be used alone.

Description

Technical field: [0001] The invention belongs to the technical field of western medicine, and relates to a flunarizine hydrochloride injection and a preparation method for treating chronic vascular disease, peripheral vascular disease, central or peripheral vertigo, and having good curative effect on chronic cold urticaria. Background technique: [0002] The existing flunarizine hydrochloride only has oral capsules, which not only has low bioavailability and slow absorption, but also is very difficult for critically ill patients to take orally. Invention content: [0003] The purpose of the present invention is to develop a flurazine hydrochloride injection, which has good curative effect, quick onset, wider therapeutic range than capsules, and plays a positive role in the rescue of acute, critical and critical patients. [0004] The technical scheme adopted in the present invention is that flunarazine hydrochloride, benzyl alcohol solution, 1,2-propanediol solution, and a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/495A61P9/00A61P37/08A61P43/00
Inventor 曹长城余帮海王国范李玉玺
Owner 曹长城
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