Method for preparing optical pure phenylethanediol by utilizing microbial stereoselectivity transformation and its special-purpose microbe

A technology of pure phenylethylene glycol and phenylethylene glycol, applied in fermentation, bacteria, etc., can solve the problems of low optical purity of products
CN1477203AActive Publication Date: 2004-02-25JIANGNAN UNIV
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Patent Information

Authority / Receiving Office
CN Β· China
Current Assignee / Owner
JIANGNAN UNIV
Publication Date
2004-02-25
Patent Text Reader

Abstract

The present invention relates to a method for preparing optical pure phenyl ethanediol by utilizing microbial stereoselective conversion and its special-purpose microbe. It utilizes the screening process to obtain two strains of Candiba parapsilosis CCTCC M203011 and Bacillus polymyxa CCTCC M203010. Two strains can be used to make asymmetric conversion of racemic phenyl ethanediol so as to obtainthe product (S)-phenyl ethanediol, its optical purity is higher. Besides, it also provides optimized culture medium composition, culture condition, reaction system and reaction condition.
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Description

technical field

[0001] The invention discloses a method for preparing optically pure phenylethylene glycol by stereoselective conversion of microorganisms and special microorganisms thereof, belonging to the technical field of biological separation of racemic compounds. Background technique

[0002] Optically pure phenylethylene glycol, that is, (S)-phenylethylene glycol, also known as (S)-PED, is not only an indispensable and important chiral additive in liquid crystal materials, but also has become a As an important intermediate of medicine, pesticide and functional materials, it is very meaningful to carry out research on the resolution method of phenylethylene glycol.

[0003] Chiral compounds play an important role in people's lives. Since the two enantiomers are different in pharmacology, toxicology and functional effects, the preparation of optically pure chiral modular compounds is very important in medicine, agriculture, materials and Environmental protection and o...

Claims

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