Astragalus root extract injection and its preparation method

A kind of Radix Astragali injection, technology of Radix Astragali, applied in the field of injection

Inactive Publication Date: 2004-07-28
SHANGHAI SHENGPING MEDICINE SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, the current small-volume Astragalus injection and the traditional method of adding it to large-capacity injections to form large-capacity Astragalus injections cannot meet people's needs, and it is extremely necessary to develop a large-capacity Astragalus injection.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Add 12kg of water to 1000g Astragalus membranaceus, decoct for 0.5h, filter, repeat 4 times, combine the filtrate, concentrate the filtrate to 2g Astragalus membranaceus / ml, add ethanol to make the alcohol content reach 75wt%, place at 4°C for 48h, filter, Recover ethanol under reduced pressure, concentrate to 5.0g Astragalus membranaceus / ml, add ethanol to make the alcohol content reach 85wt%, refrigerate for 12h, filter, recover ethanol under reduced pressure, concentrate to 10g Astragalus membranaceus / ml, add water to dilute to 1.0g Astragalus membranaceus / ml, Refrigerate for 4 hours, filter, concentrate under reduced pressure to 5.0g Astragalus membranaceus / ml, put it on the macroporous resin of ZTC type, rinse with 500ml of water, 500ml of NaOH solution with a concentration of 0.1wt%, and 200ml of ethanol with a concentration of 30wt% , discard the eluate, then elute with a concentration of 70wt% ethanol, collect the precipitated liquid until no saponin reaction, an...

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PUM

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Abstract

The present invention discloses an astragalus injection and its preparation method. Decocting astragalus root in water, filtering, reduced pressure concentrating filtrate, adding ethyl alcohol, standing still, filtering reduced pressure concentrating, adding water to make dilution, cold storing, filtering, reduced pressure concentrating, using macroporous resin to make separation, collecting eluent, using water to make dilution, adding L-arginine, regulating pH to 7.0-7.5, adding active carbon, filtering to remove carbon, adding water to make dilution so as to obtain the invented astragalus injection.

Description

technical field [0001] The invention relates to an injection prepared from active ingredients extracted from Chinese herbal medicines, in particular to astragalus injection and a preparation method thereof. Background technique [0002] The root extract of Astragalus membranaceus is a Chinese herbal medicine that has the functions of nourishing qi and nourishing energy, strengthening the body and removing pathogenic factors, nourishing the heart and opening the channels, invigorating the spleen and removing dampness. Insufficient function and hepatitis due to spleen deficiency and dampness. At present, the commercially available Astragalus injection is a small-dose injection, and what is still used is the Chinese medicine standard (1998) of the Ministry of Health of the People's Republic of China. It is 2ml, which is equivalent to 4g of the original medicinal material, or 10ml, which is equivalent to 20g of the original medicinal material . [0003] Relevant data show that...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61P1/16A61P31/12
Inventor 蔡国琴
Owner SHANGHAI SHENGPING MEDICINE SCI & TECH
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