27 results about "Astragalus Root Extract" patented technology

The invention discloses a preparation method of an astragalus extract with a uric acid reducing effect, and belongs to the technical field of biological medicines. The method comprises the following steps: concentrating an ethanol extract of radix astragali, extracting by using n-butyl alcohol, ethyl acetate and petroleum ether respectively, and concentrating an extract to obtain n-butyl alcohol, ethyl acetate and petroleum ether extraction parts and residual parts respectively, so as to obtain an n-butyl alcohol extract, namely the radix astragali extract for reducing uric acid. Efficacy experiments show that the normal butanol extraction part of the ethanol extract of the astragalus membranaceus can obviously reduce the serum uric acid level (SUA) of a mouse with hyperuricemia, inhibit the activity of xanthine oxidase (XOD) and effectively improve kidney injury caused by the hyperuricemia. The uric acid reducing effect of the radix astragali n-butyl alcohol extract is close to that of a clinical drug allopurinol, and the radix astragali n-butyl alcohol extract has wide development and application prospects in the aspect of relieving hyperuricemia.

This invention belongs to the field of plant extract technology, specifically relating to a plant extract composition for enhancing immunity. By weight, it is composed of the following raw materials: 3-5 parts Astragalus membranaceus extract, 2.5-4 parts Echinacea purpurea extract, and 1.5-3.5 parts Rhodiola rosea extract. This plant extract composition, through the scientific formulation of Astragalus membranaceus, Echinacea purpurea, and Rhodiola rosea, and an enzymatic extraction process, enhances the immunomodulatory effect. The combination of the three extracts increases the secretion of TNF-α and IL-6 by macrophages. Furthermore, the spleen lymphocyte stimulation index (SI) of the three extracts reaches 5.57, and the lymphocyte transformation rate increases from 191% to 457%. These results indicate that this plant extract composition effectively enhances the body's non-specific and cellular immune functions by activating macrophages and promoting T lymphocyte proliferation through multiple pathways, providing more comprehensive immune protection.

The invention provides a composition with an effect of improving iron-deficiency anemia as well as a preparation method and application of the composition, and belongs to the technical field of pharmaceutical compositions. The composition with the effect of improving iron-deficiency anemia, provided by the invention, is prepared from the following raw materials in parts by weight: 15 to 20 parts of radix astragali seu hedysari extract, 5 to 10 parts of fructus jujubae extract, 2 to 5 parts of radix paeoniae alba extract, 4 to 8 parts of radix angelicae sinensis extract and 8 to 16 parts of ethylenediaminetetraacetic acid ferric sodium salt. The defect of single effect in the prior art is broken through, the synergistic effect of the four effects of improving iron-deficiency anemia, helping sleep, improving acne and protecting gastric mucosa is achieved through scientific compatibility, the conditioning requirements of crowds with multiple diseases can be met without taking multiple products, the eating burden is reduced, meanwhile, the antagonistic effect among different product components is avoided, and the health-care product is suitable for being popularized and applied. The overall conditioning effect can be improved.

The invention relates to the technical field of functional food preparation, in particular to a composition capable of improving colitis and a preparation method thereof, and the composition comprises glutamine, a composite plant extract, a zinc source and soluble dietary fibers. Wherein the compound plant extract comprises hericium erinaceus extract, ginseng extract and astragalus extract; the zinc source is zinc glycinate, zinc gluconate and the like; the soluble dietary fiber is fructo-oligosaccharide, inulin, galactomannan oligosaccharide and the like. The preparation method comprises the following steps: directly carrying out dry mixing or carrying out fluidized bed granulation on glutamine to obtain particles A, mixing the composite plant extract and the dietary fibers with ethanol, carrying out spray drying to obtain particles B, and carrying out three-dimensional mixing on the particles B and the zinc source. The composition can maintain the homeostasis of intestinal epithelial cells, reduce oxidative stress and inflammatory response, promote mucosal repair and effectively improve ulcerative colitis, Crohn's disease and chemoradiotherapy-related intestinal mucositis through multi-target action.

This invention relates to a method for preparing and applying a composition for promoting growth and reducing inflammation in laying chicks, belonging to the field of veterinary feed additives. The components and their weight ratios are as follows: 20-30 parts of Codonopsis pilosula extract, 15-25 parts of Astragalus membranaceus extract, 10-20 parts of Tartary buckwheat extract, 10-20 parts of Elsholtzia ciliata extract, 3-5 parts of zinc sucrose, 2-3 parts of emulsifier, and 1-2 parts of stabilizer. First, the four extracts of Codonopsis pilosula, Astragalus membranaceus, Tartary buckwheat, and Elsholtzia ciliata are concentrated, spray-dried, and then mixed evenly with zinc sucrose, emulsifier, and stabilizer using a three-dimensional mixer to obtain the composition for promoting growth and reducing inflammation in laying chicks. This composition can significantly improve the growth performance of laying chicks, enhance their immunity, effectively prevent and control inflammatory responses, and improve survival rate and feed conversion rate. It is suitable for laying chick farming and has broad market application prospects.

The invention discloses a composition containing an astragalus extract as well as a preparation method and application of the composition. The composition comprises a carrier layer, a core functional layer, an assistant functional layer, a functional powder layer and a probiotic layer from inside to outside. According to the invention, monarch and ministerial drugs (astragalus membranaceus, codonopsis pilosula, bighead atractylodes rhizome and poria cocos) are taken as a core layer through a fluidized bed, adjuvant and conductant drugs (isatis root, dandelion and platycodon grandiflorum) are taken as a secondary layer, sequence batch layering is realized, and directional release can be realized.

The invention discloses an anti-radiation organic selenium salt and a preparation method and application thereof in the field of functional food additives. The anti-radiation organic selenium salt is prepared from the following components in percentage by weight: basic salt: 80-95% of lake salt, rock salt, bamboo salt, sea salt or refined table salt; the organic selenium active ingredients comprise 0.1 to 2 percent of L-selenomethionine, and / or 1 to 3 percent of selenium-enriched yeast extract, and / or 0.5 to 2 percent of selenized carrageenan. Through fluidized bed coating and microcapsule technologies, the six-month selenium retention rate is greater than or equal to 95%, the problem that organic selenium is easy to degrade is solved, the stability is high, L-selenomethionine and vitamin E cooperate, and simulated digestion experiments show that the selenium bioavailability is greater than or equal to 80% and is superior to that of inorganic selenium (lt); 50%); the organic selenium scavenges free radicals, the vitamin E protects cell membranes, and the zinc and the astragalus extract enhance immunity, so that all-around radiation protection is realized; the amino acid mixture covers the bitter taste of the organic selenium, the delicate flavor score is greater than or equal to 7.5 / 10, and the palatability is good; the method can be directly integrated to an existing salt production line, and is suitable for industrial production.

The invention relates to the technical field of feed additives, and discloses a Liaoning medicinal plant extract compound feed additive, which is prepared by the following steps: uniformly mixing an acanthopanax senticosus extract, a schisandra chinensis extract, an astragalus membranaceus extract, ginseng polysaccharide and ginsenoside to obtain a compound plant extract; stearic acid and soya bean lecithin are adopted to coat the composite plant extract to form lipid nanoparticles; and mixing the lipid nanoparticles with the composite carrier, and sieving to obtain the composite feed additive. The lipid nanoparticles are loaded on the composite carrier, so that the formed composite feed additive is not easily influenced by environmental factors such as light, heat and oxygen, has relatively high activity, improves the quality of feed and the appetite of bred livestock and poultry, is relatively high in bioavailability, and improves the meat growth speed of the bred livestock and poultry.

This invention provides a plant extract complex for wrinkle reduction and fine line removal, its preparation method, and its application, relating to the cosmetics field. The plant extract complex of this invention comprises the following raw materials in parts by weight: 3-7 parts of Centella asiatica extract, 2-4 parts of ginseng root extract, 2-3 parts of Astragalus membranaceus extract, 1-2 parts of grape seed extract, 1-2 parts of camellia flower extract, 0.5-1.5 parts of white tea extract, 0.5-1.5 parts of green tea extract, 0.5-1 part of Kakadu plum fruit extract, 0.3-1 part of holy basil leaf extract, 0.2-0.8 parts of broccoli bud extract, and 0.2-0.4 parts of guarana fruit extract. The product prepared by this invention possesses excellent anti-wrinkle and firming effects, good biocompatibility, and can effectively reduce wrinkles and fine lines.

The invention relates to a spraying type composition for protecting heart and cerebral vessels as well as a preparation method and an application method thereof, and belongs to the technical field of health-care medicines. A formula of the injection type composition for protecting the heart and cerebral vessels comprises the following components in parts by weight: 10-30 parts of a radix astragali extract, 10-30 parts of a rhizoma atractylodis macrocephalae extract, 10-30 parts of a rhizoma polygonati extract, 5-20 parts of a cortex eucommiae extract, 10-30 parts of an oyster extract, 5-20 parts of a herba cistanche extract and 5-10 parts of a composite penetrant. Wherein the formula of the composite penetrating agent comprises the following components in parts by weight: 0.5-1 part of a clove extract, 0.5-2 parts of a pepper extract and 2-9 parts of a chemical penetration enhancer; the composition prepared by the invention has the characteristics of efficient permeability and heart and cerebral vessel protection.

The invention relates to the technical field of veterinary drugs, in particular to a composition for preventing and / or treating donkey mastitis and application thereof. The invention provides a composition for preventing and / or treating donkey mastitis. The composition comprises the following components: nisin, lysozyme, a honeysuckle extract, a dandelion extract, a lithospermum extract, an astragalus extract and a frankincense extract. The composition can effectively prevent and / or treat donkey mastitis, the active ingredients of the composition are natural or biogenic substances, the antibacterial mechanism of the composition is unique, bacteria are not easily induced to generate drug resistance, and the composition is safe and free of residues, meets the urgent needs of green, healthy and sustainable development of animal husbandry, and has remarkable clinical application value and wide market prospects.

The invention provides a hirudin penetration-promoting herbal compound body fat health-care liquid as well as a preparation method and application thereof, and the hirudin penetration-promoting herbal compound body fat health-care liquid comprises the following raw materials in percentage by weight: 0.3-0.6% of a leech extract, 0.3-0.6% of a Chinese herbal medicine extract and the balance of water. 5-10% of a herbal compound extract; 0.3 to 0.5 percent of methyl salicylate; 0.2 to 0.4 percent of ginger root oil; 8-12% of ethanol; and the balance of water. Wherein the herbal compound extract comprises an aloe vera extract, an astragalus membraneus extract, a ginseng extract and a panax notoginseng leaf and stem extract. According to the invention, a three-in-one technical system of efficient permeation promotion, multi-element conditioning, stability and mildness is constructed, the technical bottlenecks of low transdermal efficiency, single effect and insufficient stability of a traditional external herbal product are broken through, and the synergistic gain of body fat conditioning and skin repair is realized.

The invention discloses a live fish waterless transportation method based on a composite functional bag, and relates to the technical field of aquatic living body transportation. Comprising the following steps: (1) temporary rearing treatment before transportation; (2) water-free oxygenation packaging; (3) carrying out heat-preservation transportation; (4) resuscitating in a pond; the bag A is an adsorption slow-release bag and comprises a compound of a beta-cyclodextrin embedded astragalus extract concentrated solution, a honeysuckle extract concentrated solution and L-menthol, and activated carbon; the bag B is an immunological enhancement bag and comprises chondroitin sulfate, curcumin and quercetin. Through multiple mechanisms of slowly releasing anti-stress components, adsorbing metabolic waste, enhancing immunity and the like, the survival rate and health state of channel catfish, perch, pelteobagrus fulvidraco and the like in water transportation are remarkably improved, and the method has the advantages of being easy and convenient to operate, low in cost and wide in application range.

The application discloses a culture medium and a culture method for preparing umbilical cord mesenchymal stem cell exosomes. The culture medium for preparing umbilical cord mesenchymal stem cell exosomes is composed of 99.79-99.99 wt% mesenchymal stem cell serum-free culture medium and 0.01-0.21 wt% additional agent; the additional agent is cyclodextrin modified astragalus extract; and the cyclodextrin modified astragalus extract is obtained by reaction of organic acid modified cyclodextrin and astragalus extract. The application also provides a preparation method thereof. Compared with the prior art, the culture medium for preparing umbilical cord mesenchymal stem cell exosomes has the advantages of good culture medium stability, can promote the proliferation of mesenchymal stem cells, and can effectively induce human umbilical cord mesenchymal stem cells to synthesize and secrete exosomes in large quantities.

This invention relates to the field of cosmetic technology, and more particularly to a sensitive skin anti-wrinkle barrier repair composition containing purslane extract and its application. The composition of this invention comprises purslane extract, astragalus extract, centella asiatica extract, ectoine, and ceramide complex lipids; the ceramide complex lipids include one or more of ceramides, cholesterol, and fatty acids. This invention uses purslane extract as a soothing and stabilizing base, combined with astragalus extract, centella asiatica extract, ectoine, and ceramide complex lipids to form a complex care system that combines soothing, anti-wrinkle, barrier repair, and improved skin tolerance. Experimental results show that the composition of this invention can improve problems such as fine lines, dry lines, redness, stinging, fragile barrier, dryness, tightness, and decreased tolerance in sensitive skin. It is gentle, stable, and can be prepared into various cosmetic formulations such as face cream, serum, lotion, repair cream, sleeping mask, essence, and gel cream, suitable for industrial production and daily skincare use.

The invention discloses a composition for improving functions of myocardial cells and application of the composition. The composition comprises the following components: procyanidine, inulin, an astragalus extract and a seville orange flower extract. The composition belongs to the technical field of medicine and health care, all the components in the composition have a synergistic effect, the antioxidant effect can be comprehensively achieved, meanwhile, the intestinal function is improved, the constipation treatment effect is enhanced, the myocardial infarction area is remarkably reduced, and the curative effect is good. The myocardial cell function is comprehensively improved from the aspects of tonifying qi and blood, inhibiting oxygen free radicals, improving constipation and the like, and the compound can be applied to preparation of drugs for preventing or treating cardiovascular diseases such as myocardial infarction.

This invention provides a method for preparing Astragalus extract for anti-liver aging and its application, belonging to the field of natural product extraction and biomedicine technology. The invention uses a water extraction method to prepare Astragalus polysaccharide extract. The core steps are: pulverizing dried Astragalus, soaking in deionized water at a material-to-liquid ratio of 1:10 to 1:15 for 24 hours, extracting at 90℃ to 100℃ for 2 to 3 hours, filtering, concentrating to 1 / 4 of the original volume, and drying to obtain Astragalus polysaccharide powder. This invention also discloses the application of the Astragalus polysaccharide extract in the preparation of anti-liver aging products. The preparation process of this invention is simple, low-cost, and can be mass-produced. The obtained product has stable activity and controllable quality, and can significantly reduce fat deposition in aging livers, increase the activity of liver SOD and GSH-Px antioxidant enzymes, effectively delaying liver aging, and has good application prospects. The pure water extraction method for preparing the core active ingredient of Astragalus polysaccharide eliminates the need for large amounts of toxic organic solvents, making it environmentally friendly, with fewer operation steps and a simpler process, significantly reducing production costs.

The present application relates to the technical field of water extraction and alcohol precipitation, in particular to a kind of astragalus membranaceus subsection drying combined enzymatic hydrolysis auxiliary water extraction and alcohol precipitation process, comprising the following steps: after being cleaned and impurity-removed, fresh astragalus membranaceus is classified according to diameter and sliced;Based on classification data, astragalus membranaceus slices are dried to target moisture content in low-temperature and low-humidity environment;Moisture content data based on real-time monitoring data start moderate temperature drying;According to the moisture content after drying, the crushing intensity is dynamically adjusted.The present application realizes accurate matching of drying parameters by raw material classification and moisture content filing, and the subsection drying strategy protects the structure of heat-sensitive components intact, and the enzymatic hydrolysis auxiliary wall breaking significantly improves the dissolution rate of active ingredients, and the gradient alcohol precipitation technology realizes targeted removal of impurities and efficient recovery of target components, the whole process data linkage control eliminates human operation error, solvent closed-loop recovery reduces production cost, and finally obtains high-purity, high-yield and stable quality astragalus membranaceus extract, which breaks through the technical bottleneck of traditional process.

The invention discloses a crataegus pinnatifida roxburgh rose peptide beverage, which is prepared from the following raw materials in parts by mass: 100 parts of roxburgh rose normal juice, 12 to 14 parts of giant salamander peptide, 4.5 to 5.5 parts of fructus crataegi extract, 2.5 to 3.0 parts of rhizoma dioscoreae extract, 2.0 to 2.5 parts of radix astragali seu hedysari extract, 1.8 to 2.2 parts of folium cortex eucommiae extract, 60 to 70 parts of water, 0.9 to 1.1 parts of locust bean gum and 0.03 to 0.05 part of stevioside. Artificial sweeteners and preservatives are not added into the beverage, the sweet taste comes from natural stevioside, the system is stable and depends on natural locust bean gum, the natural properties of the raw materials are reserved, and the beverage conforms to the consumption trend of consumers for healthy and natural beverages.

The invention belongs to the field of bioactive preparations and tissue regeneration, and particularly discloses herbal active hair growth liquid as well as a preparation method and application thereof. The herbal active hair growth liquid is prepared by compounding deionized water, medicinal-grade butanediol, an astragalus membranacus root extract, a ganoderma atrum extract, an angelica sinensis root extract, a cordyceps sinensis extract, a ginseng extract and phenoxyethanol according to a specific weight percentage, dissolving, stirring, controlling the temperature, monitoring the particle size, defoaming and the like. The herbal active hair growth liquid prepared by the invention can remarkably promote proliferation of human hair follicle outer root sheath cells, can realize complete hair regeneration, remarkably increases the number of hair follicles and the diameter of the hair follicles, is superior to existing products, and is suitable for industrial production and application.

The invention discloses a snake accompanying 500 with telomere repairing function and a preparation method thereof, the product is prepared by taking white spirit as a main material and adding an agkistrodon halys extract, a zaocys dhumnade extract, 1-3% of agkistrodon halys meat protein, 2-4% of zaocys dhumnade meat protein, a green tea extract, an astragalus extract and a carrot extract as auxiliary materials; the preparation method comprises the following steps: pretreating, soaking, clarifying, filtering, blending, storing and packaging. The method is simple and suitable for industrialization and large-scale production, the garter snake and the agkistrodon halys are used as main raw materials, a good telomere repairing effect is achieved after long-term drinking, and the life can be prolonged.

The invention provides a nursing pharmaceutical composition for preventing pressure sores and a preparation method thereof, and the composition is composed of an active component, a liquid absorption component and pharmaceutically acceptable auxiliary materials, active components of the composition comprise an astragalus extract, an angelica sinensis extract, a lithospermum extract, a recombinant human epidermal growth factor, pentoxifylline, polyhexamethylene biguanide hydrochloride, beta-glucan, asiaticoside and magnolol, and the effects of improving microcirculation, resisting inflammation and bacteria and promoting tissue repair are comprehensively achieved through a multi-target synergistic effect; luminan microspheres or calcium alginate fibers are adopted as liquid absorption components, wound exudate is effectively managed, a wet environment is maintained, a split-phase preparation and low-temperature integration process is adopted in the preparation method, the compatibility problem of complex components is solved, and the stability and effectiveness of the product are ensured; the device integrates active treatment and protection, is suitable for preventing and treating pressure sores in all stages, and has the advantages of being remarkable in effect and safe to use.

This invention provides Astragalus exosomes with anti-breast cancer and anti-lung cancer effects, their preparation method, and applications, relating to the field of biomedical technology. The preparation method of the Astragalus exosomes includes the following steps: Astragalus root is soaked in physiological saline to obtain an Astragalus suspension; homogenization and centrifugation are performed to obtain supernatant 1, which is then filtered through a filter membrane to obtain supernatant 2; tangential flow filtration and concentration are performed: supernatant 2 is continuously filtered and concentrated through a 0.15-0.3 μm tangential flow filtration membrane assembly, the permeate is collected, and the retained material is discarded; the permeate is then continuously filtered and concentrated through a 0.015-0.025 μm tangential flow filtration membrane assembly, the retained liquid is collected, and the permeate is discarded; the retained liquid is filtered through a 100-300 kDa ultrafiltration membrane to retain the exosomes, and the concentration is performed to obtain a concentrated solution; washing, filtration, purification, and sterilization are then performed. The Astragalus exosomes prepared by this invention have significant inhibitory effects on both breast cancer and lung cancer, solving the problems of unclear anti-cancer active ingredients and low utilization rate of traditional Astragalus extracts.

The invention provides an astragalus membranaceus exosome with anti-breast cancer and anti-lung cancer effects as well as a preparation method and application thereof, and relates to the technical field of biological medicines. The preparation method of the astragalus membranaceus exosome comprises the following steps: adding normal saline into astragalus membranaceus roots, and soaking to obtain astragalus membranaceus suspension; homogenizing and centrifuging to obtain a supernatant 1, and filtering with a filter membrane to obtain a supernatant 2; carrying out tangential flow filtration and concentration, namely continuously filtering and concentrating the supernate 2 through a 0.15-0.3 mu m tangential flow filtration membrane assembly, collecting permeate liquid, and discarding retentate; continuously filtering and concentrating the permeate through a tangential flow filtering membrane assembly with the size of 0.015-0.025 mu m, collecting trapped fluid, and discarding the permeate; filtering the trapped fluid through a 100-300kDa ultrafiltration membrane, trapping exosomes, and concentrating to obtain a concentrated solution; and washing, filtering, finely purifying and sterilizing. The astragalus membranaceus exosome prepared by the invention has a remarkable inhibition effect on breast cancer and lung cancer, and solves the problems that the traditional astragalus membranaceus extract is indefinite in anticancer active ingredient and low in utilization rate.

The invention belongs to the field of health-care food, and relates to a radix puerariae extract composition for preventing and treating diabetic complications and a preparation method thereof, radix puerariae extract rich in puerarin is matched with radix astragali extract and mulberry leaf extract, antioxidants such as coenzyme Q10 and alpha-lipoic acid are added, probiotics are further compounded, and an optimized preparation process of the composition is provided. Comprising combined extraction, purification and microencapsulation technologies of specific parameters. The product provided by the invention provides a composition with multi-component and multi-target synergistic effect, is high in safety and suitable for long-term administration, has stable utilization of active ingredients, provides a new solution for prevention and adjuvant therapy of diabetic complications, and has intervention potential for diabetic complications.

The invention discloses a mouth spray containing a black ginseng extract and a preparation method of the mouth spray. The oral spray is prepared from the following components in percentage by mass: 5 to 30 percent of radix scrophulariae extract, 0.1 to 2 percent of guarana extract, 0.05 to 1 percent of herba menthae extract, 0.05 to 1 percent of folium artemisiae argyi extract, 0.1 to 3 percent of radix astragali seu hedysari extract, 0.1 to 3 percent of flos chrysanthemi extract, 15 to 30 percent of humectant, 0.5 to 5 percent of emulsifier and the balance of water. Wherein the black ginseng extract is prepared from lactobacillus plantarum, lactobacillus rhamnosus and streptococcus thermophilus through solid pre-fermentation and multi-round steaming-synchronous fermentation. Through synergistic interaction of multiple plant extracts and combination of a split-phase preparation process, the natural oral spray which can be rapidly absorbed through oral mucosa, has mild and lasting refreshing effects and is good in stability, good in taste and suitable for relieving fatigue and improving attention is obtained.

This invention discloses a fermented soybean meal feed and its preparation method, belonging to the field of fermented feed technology. The feed includes soybean meal, barley flour, wheat bran, sorghum flour, rice bran polysaccharide, compound vitamins, dicalcium phosphate, sodium chloride, microbial stress tolerance enhancer, compound enzyme preparation, fructooligosaccharide, inulin, honeysuckle extract, astragalus extract, and compound microbial agent. In preparation, the grain raw materials are pulverized and mixed with rice bran polysaccharide, etc., to obtain the fermentation raw material. The compound microbial agent and microbial stress tolerance enhancer are activated in warm water containing brown sugar and then sprayed onto the fermentation raw material. After adjusting the moisture content, the mixture is sealed for fermentation, dried, and pulverized. Finally, fructooligosaccharide, inulin, and plant extracts are added and mixed thoroughly. Compared with existing technologies, this invention effectively protects the activity of the compound microbial agent during fermentation and drying, significantly improves the retention rate of live bacteria and the storage stability of the product, and the process is simple and cost-controllable.