Chinese traditional medicine composition for treating diabetic nephropathy

Abstract

The invention relates to a Chinese traditional medicine composition for treating diabetic nephropathy which comprises raw astragalus root, prepared aconite root, and prepared rhubarb, the medicine can also comprise other compositions including notoginseng, root of red rooted saliva, achyranthes and cyathula root, gen-seng, pseudostellaria root, pilose asiabell root, Poria cocos, Poria cocos.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating diabetic nephropathy. Background technique [0002] Diabetic nephropathy (DN) is the most common complication of diabetes and one of the leading causes of death in diabetic patients. With the improvement of living standards in our country, the incidence of diabetes, especially type 2 diabetes, is increasing year by year, and the incidence of DN is increasing year by year. The total incidence is as high as 40%. [0003] The etiology and pathogenesis of DN are very complex, in addition to genetic factors, it also involves metabolism, hemodynamics, related growth factors, cytokines and many other aspects. The main pathological change of diabetic nephropathy is excessive accumulation of matrix protein in glomerular mesangial cells, followed by glomerulosclerosis and tubulointerstitial fibrosis. Studies at home and abroad have shown that transforming growth factor-β 1 (TGF-β...

AI Technical Summary

Problems solved by technology

Although the large compound formula has good clinical curative effect, it is very difficult to elucidate its therapeutic mechanism; most of the single herbal medicines or monomers are in the stage of experimental research, and because they do not have the advantage of compatibility of traditional Chinese medicine, the clinical curative effect is mostly unsatisfactory