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Polyinosinic powder for livestock and preparation method thereof

A technology of livestock and poultry and polyinosinic acid, which is applied in the field of polyinosinic acid dry powder and its preparation, can solve the problems of livestock and poultry stress, disease recovery that affects growth and development, etc., to reduce morbidity, protect virus damage, and reduce mortality Effect

Inactive Publication Date: 2010-06-30
TIANJIN RINGPU BIO TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It is mainly used to treat viral diseases in veterinary clinics, and its dosage form is mainly injections. However, the use of injections often causes stress to livestock and poultry, directly affecting their growth and recovery from diseases.

Method used

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  • Polyinosinic powder for livestock and preparation method thereof
  • Polyinosinic powder for livestock and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Embodiment 1: 0.5 part of polyinosinic acid, 0.5 part of polycytidylic acid, Na 2 HPO 4 .2H 2 O buffer 0.05 parts, NaH 2 PO 4 .12H 2 O0.7 part, NaCl 1 part, oral glucose added to 100 parts. Take NaH 2 PO 4 .12H 2 O, Na 2 HPO 4 .2H 2 O and NaCl were dissolved in water for injection respectively, mixed evenly and diluted to 1000ml with water for injection, and the measured pH value should be 7.2±0.2. Take 50ml of the above buffer solution preheated to 45°C in two containers, add polyinosinic acid and polycytidylic acid respectively, stir and dissolve, keep warm in a water bath at 45°C for 30 minutes, combine the two liquids in one of the containers, and use a small amount of buffer Rinse another container with washing liquid, add the washing liquid into the above solution, and keep warm at 45°C for 40 minutes again, and keep stirring gently during the heat preservation process. Combine the solutions after the above-mentioned incubation, and dilute to 200ml wit...

Embodiment 2

[0052] Embodiment 2: 10 parts of polyinosinic acid, 10 parts of polycytidylic acid, Na 2 HPO 4 .2H 2 2.5 parts of O buffer solution, NaH 2 PO 4 .12H 2 O3 parts, NaCl 5 parts, lactose added to 100 parts. Take NaH 2 PO 4 .12H 2 O, Na 2 HPO 4 .2H 2 O and NaCl were dissolved in water for injection respectively, mixed evenly and diluted to 1000ml with water for injection, and the measured pH value should be 7.2±0.2. Take 50ml of the above buffer solution preheated to 45°C in two containers, add polyinosinic acid and polycytidylic acid respectively, stir and dissolve, keep warm in a water bath at 45°C for 30 minutes, combine the two liquids in one of the containers, and use a small amount of buffer Rinse another container with washing liquid, add the washing liquid into the above solution, and keep warm at 45°C for 40 minutes again, and keep stirring gently during the heat preservation process. Combine the solutions after the above-mentioned incubation, and dilute to 200...

Embodiment 3

[0054] Embodiment 3: 20 parts of polyinosinic acid, 20 parts of polycytidylic acid, Na 2 HPO 4 .2H 2 5 parts of O buffer solution, NaH 2 PO 4 .12H 2 5 parts of O, 10 parts of NaCl, and 100 parts of starch. Take NaH 2 PO 4 .12H 2 O, Na 2 HPO 4 .2H 2 O and NaCl were dissolved in water for injection respectively, mixed evenly and diluted to 1000ml with water for injection, and the measured pH value should be 7.2±0.2. Take 50ml of the above buffer solution preheated to 45°C in two containers, add polyinosinic acid and polycytidylic acid respectively, stir and dissolve, keep warm in a water bath at 45°C for 30 minutes, combine the two liquids in one of the containers, and use a small amount of buffer Rinse another container with washing liquid, add the washing liquid into the above solution, and keep warm at 45°C for 40 minutes again, and keep stirring gently during the heat preservation process. Combine the solutions after the above-mentioned incubation, and dilute to ...

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Abstract

The invention aims to provide veterinary polyinosinic powder which mainly comprises poly cytidine acid, poly inosinic acid and auxiliary material, is prepared through a series of processes, such as mixing, dissolving, granulating, drying, grinding and the like, and is mainly used to prevent and treat the virus diseases of the livestock. Through the clinical therapeutic effect test we find that the medicine is characterized by good therapeutic effect, little dosage and high efficiency in preventing and treating the virus diseases of the livestock, and is suitable to be popularized and applied in the livestock industry.

Description

technical field [0001] The invention belongs to the field of veterinary medicine, in particular to a polymyocyte dry powder for livestock and poultry and a preparation method thereof. Background technique [0002] Infectious diseases of livestock and poultry are the most serious diseases to the breeding industry, causing a lot of losses to the livestock breeding industry. The hazards of viral infectious diseases are particularly serious. Infectious diseases can also pose a serious threat to human health. In the modern breeding industry, the herds are highly concentrated, and the transportation is frequent, so they are more vulnerable to the invasion of viral diseases. Therefore, the prevention and research of livestock and poultry viral diseases have always been valued by countries all over the world, and they occupy the first place in veterinary science and technology research. [0003] At present, the prevention and treatment of viral diseases in livestock and poultry ma...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7088A61K9/14A61P31/12
Inventor 李旭东苏建东刘菁
Owner TIANJIN RINGPU BIO TECH
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