Yujin drop pill for clearing away the heat-evil and expelling superficial evils and its preparation method

The technology of Jin dripping pills and honeysuckle flower is applied to the Yujin dripping pills used for clearing away heat and detoxification and the field of preparation thereof, which can solve the problems of long time limit for dissolving and dispersing, which is not conducive to improving the ability of patients to seek medical treatment, and the dissolution rate is low. Symptoms of irritation, improved bioavailability, and accelerated dissolution and absorption

Inactive Publication Date: 2005-07-06
北京正大绿洲制药有限公司
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AI Technical Summary

Problems solved by technology

[0013] In addition, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking, which affect the quality of the drug. Efficacy, also directly affects the therapeutic effect Conventional oral dosage forms, such as tablets, capsules, etc.
In addition, due to the granulation process in the preparation proces

Method used

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Examples

Experimental program
Comparison scheme
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Embodiment Construction

[0040] Now with several groups of specific examples, the preparation method of the Yujin Dropping Pills of the present invention will be further described.

[0041] Group 1: Tests with a single matrix

[0042] 1. Weigh a certain amount of traditional Chinese medicine raw materials according to the ratio given in [Preparation Method] 1, and then prepare the extract containing pure Chinese medicine active ingredients of Houttuynia cordata and honeysuckle according to the section [Appendix: A preparation method of a Chinese medicine extract] Thick paste, or dried under low temperature and reduced pressure, crushed to obtain dry powder for later use;

[0043] 2. Base: polyethylene glycol (1000-20000), polyoxyl 40 stearate, beta-cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid , sodium stearate, glycerin gelatin, shellac and other pharmaceutically acceptable carriers;

[0044] 3. Proportion—in g or kg, in parts by weight, drug extract: mat...

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Abstract

The invention discloses a milt drop pill for treating upper respiratory tract infection, bronchopneumonia, virus pneumonia, purulency diseases, and gynaecologic diseases. The drop pill is prepared through the conventional injection extracting processes, which has the advantages of high biological availability, quick-speed medicine release, quick-speed effect, less toxic and side effects, higher medicinal content, smaller amount of administration, accurate administration dosage, easy administration, low price, and facilitated carrying.

Description

technical field [0001] The present invention relates to a kind of medicine composition that has the function of clearing heat and detoxifying, and is used for the treatment of upper respiratory tract infection, bronchial pneumonia, viral pneumonia, suppurative disease, gynecological inflammation and postoperative fever caused by excessive heat and toxin. Based on traditional Chinese medicine prescription Yujin injection, a pharmaceutical composition oral drop pill preparation is formulated through dosage form modification and administration route. Background technique [0002] According to the ministerial drug standard WS 3 -Yujin injection prepared according to the formula and extraction process given in B-3263-98, is a kind of heat-clearing and detoxifying solution; it is used for upper respiratory tract infection, bronchial pneumonia, viral pneumonia, Injection preparations for the treatment of suppurative diseases, gynecological inflammation and postoperative fever have...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61P11/00A61P15/00
Inventor 曲韵智
Owner 北京正大绿洲制药有限公司
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