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Targeted controlled delivery compositions activated by changes in pH or salt concentration

A technology of composition and active agent, applied in the field of targeted control delivery composition activated by changes in pH value or salt concentration, capable of solving problems such as no targeted control delivery system

Inactive Publication Date: 2005-07-27
SALVONA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] None of the prior art known to the applicant proposes a targeted control delivery system activated by pH or salt concentration in the system environment, which can be incorporated into consumer products and various products such as fabric care, hair care and skin care products To enhance the deposition of fragrances and other active ingredients on target surfaces such as fabrics, hair, skin and other biological surfaces

Method used

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  • Targeted controlled delivery compositions activated by changes in pH or salt concentration
  • Targeted controlled delivery compositions activated by changes in pH or salt concentration
  • Targeted controlled delivery compositions activated by changes in pH or salt concentration

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0197] The following procedure was used to prepare a multi-component controlled release system using fragrance as active agent in a matrix of hydrophobic nanospheres. The nanosphere hydrophobic matrix is ​​candelilla wax, available from Strahl & Pitsch Inc. of West Babylon, New York, and the cationic conditioner is methyl bis(hydrogenated ditallow amidoethyl) 2 hydroxyethyl ammonium chloride, available as INCROSOFT 100 Available from Croda Inc. The microsphere cationic pH sensitive matrix was Eudragit® EPO (available from Rohm America Inc., Piscataway, NJ) and the water sensitive matrix was Hi-Cap TM 100 (available from National Starch and Chemical Company, Bridgewater, NJ).

[0198] 200 grams of candelilla wax was placed in an 80°C oven and allowed to melt. 1500 grams of deionized water was placed in a 1 gallon container fitted with a general purpose silicone rubber heater (Cole-Palmer Instrument Company). 300 grams of Eudragit® EPO (available from Rohm America Inc...

Embodiment 2

[0200] The following procedure was used to prepare a multi-component controlled release system using fragrance as active agent in a matrix of hydrophobic nanospheres. The hydrophobic matrix of nanospheres is polyethylene homopolymer, which can be press PERFORMALENE TM PL was purchased from New Phase Technologies, cationic conditioner was Incroquat Behenyl HE, behenyl amidopropyl hydroxyethyl dimonium chloride (a fatty quaternary ammonium salt, available from Croda), LUPASOL TM PR815, a polyethyleneimine with an average molecular weight of 1800, was used as a cationic charging aid. The microsphere cationic pH sensitive matrix was Eudragit® EPO (available from Rohm America Inc, Piscataway, NJ) and the water sensitive matrix was Hi-Cap TM 100 (available from National Starch and Chemical Company, Bridgewater, NJ).

[0201] 200 grams of polyethylene homopolymer were placed in a 90°C oven and allowed to melt. 1500 grams of deionized water was placed in a 1 gallon container fit...

Embodiment 3

[0218] Evaluation of the performance of powder laundry detergent products comprising the perfume carrier system of Example 1 (i.e. the ability to increase perfume deposition onto fabrics and prolong the release of perfume from dried laundered fabrics or on ironed fabrics over longer periods of time) ability to produce a high-pulse fragrance "burst" when tested) and compared to the performance of the same detergent containing pure fragrance. Unperfumed powdered laundry detergent base is the commodity TIDE TM FREE powdered laundry detergent, available from Procter & Gamble Company of Cincinnati, Ohio, which is fragrance free.

[0219] Laundry samples were prepared using the fragrance described in Example 1 at an effective fragrance concentration of 1%. By weighing 1 gram of pure fragrance and 99 grams of fragrance-free TIDE into the bottle TM A control sample was prepared FREE and the resulting mixture was mixed for about 1 hour. A powdered laundry detergent comprising the ...

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Abstract

The present invention relates to a novel controlled release carrier system for pH or salt triggered release and targeted delivery of fragrances and other active ingredients onto fabric, hair, skin, and other biological surfaces and which provides prolonged release of fragrances and other active ingredients over an extended period of time, or yields a high impact fragrance "burst" upon treating the target surface with heat (blow drying the hair, ironing the fabric). The controlled delivery system of the present invention is substantially a free-flowing powder formed of solid hydrophobic nano-spheres comprising the fragrance and other active ingredients that are encapsulated in a pH or salt sensitive micro-spheres. Also described are processes for preparing such compositions and processes for using same. Furthermore, certain components of the aforementioned compositions in combination with one another are novel, and other components have novel uses in increasing fragrance substantivity, particularly in fabric, hair, and skin care preparations. The invention further pertains to consumer and diversified products comprising the controlled release system of the present invention.

Description

technical field [0001] The present invention relates to a novel controlled release carrier system for the targeted delivery of fragrances and active ingredients to fabrics, hair and other biological surfaces, which is activated by changes in pH or salt concentration in the system close to the environment, and which Prolonged release of fragrance and other active ingredients over extended periods of time, or high impact fragrance "burst release" when a target surface is treated with heat, such as when drying hair or ironing fabrics. Background technique [0002] The household and cosmetic industries have for many years sought ways to enhance the performance of consumer and various products and make them aesthetically more pleasing to consumers. Consumer acceptance of consumer goods and products of all kinds is determined not only by the performance attained by these products, but also by their attendant aesthetics. In addition to imparting an aesthetically pleasing scent, fr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/51A61K8/00A61K8/04A61K8/11A61K8/31A61K8/34A61K8/37A61K8/40A61K8/49A61K8/64A61K8/65A61K8/73A61K8/89A61K8/891A61K8/97A61K8/98A61K9/50A61K47/10A61K47/14A61K47/22A61K47/24A61K47/32A61K47/34A61K47/36A61K47/38A61K47/42A61K47/46A61Q5/00A61Q5/02A61Q13/00A61Q17/04A61Q19/00C11B9/00C11D3/00C11D3/50C11D17/00
CPCC11D17/0039A61K2800/56B82Y5/00C11D3/505A61K2800/413C11D3/0047A61K8/0287A61Q13/00A61K8/0204
Inventor 阿迪·谢菲尔塞缪尔·戴维·谢菲尔
Owner SALVONA
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