Rabdosia rubescens drops and preparation thereof
A technology of Radix Oryzae and Grass Dropping Pills, which is applied in pill delivery, pharmaceutical formulations, and medical preparations containing active ingredients. Avoid gastrointestinal irritation symptoms, improve bioavailability, accelerate dissolution and absorption
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[0035] Several sets of specific examples are now used to further illustrate the preparation method of Donglingcao dripping pills of the present invention.
[0036] The first group: single matrix test
[0037] 1. Take some rubescens, chop it, add 10 times the amount of ethanol, heat and press (0.15mPa), extract for 16h, collect the extract, recover the ethanol, add 3 times the amount of medicine residue with water, decoct for 2h, filter, and combine The alcohol and water extracts are concentrated to an appropriate amount, then dried at low temperature and reduced pressure, and pulverized to obtain a dry powder.
[0038] 2. Matrix: polyethylene glycol (1000~20000) , Polyoxy 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. Medicinal carrier
[0039] 3. Proportioning—in g or kg, in parts by weight, drug extract: matrix=1:1~1:9;
[0040] 4. Then prepare according to the process ...
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