Lemai dripping pill for treating cardiovascular diseases and its preparing method

A technology of dripping pills and Lemai, which is applied in the field of Lemai dripping pills for the treatment of cardiovascular diseases and its preparation, can solve the problems of unfavorable overall health level, low dissolution rate, and unfavorable improvement of patients' ability to seek medical treatment, so as to achieve the benefits of labor Protection and environmental protection, accelerated dissolution and absorption, and improved bioavailability

Inactive Publication Date: 2005-10-19
北京博智绿洲医药科技有限公司
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AI Technical Summary

Problems solved by technology

[0007] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
Granules also have relatively low drug content, which is inconvenient to take and other deficiencies
[0008] In addition, conventional oral dosage forms, such as tablets, capsules, gra

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0028] Now with several groups of specific examples, the preparation method of Lemai dripping pills of the present invention is further described:

[0029] Group 1: Tests with a single matrix

[0030] 1. Preparation of the drug extract: according to the preparation method 1, first prepare the dry powder of the drug extract for later use;

[0031] 2. Substrate: polyethylene glycol (1000，2000、4000、6000、8000、10000，20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc.;

[0032] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0033] 4. Prepare according to the process given in [Preparation Method] 4-7 ​​to obtain Lemai Dropping Pills of different specifications.

[0034] [test results]

[0035] Experiment 1: In order to observe the difference in quality of the Lemai Dropping Pills prepared when the ratio of drug extracts...

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PUM

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Abstract

The present invention relates to a kind of medicine composition, Lemai dripping pill, with functions of activating vital energy, promoting blood circulation, alleviating mental depression, removing blood stasis, nourishing blood and dredging blood vessel and for treating coronary heart disease, atherosclerosis, pulmonary heart disease, infarct dementia, etc. The present invention has high bioavailability, fast medicine release, fast acting, high effective content, taking convenience and low cost, and the production process has no pollution. The Lemai dripping pill is prepared with seven kinds of Chinese medicinal materials, including red sage, Chuanxiong rhizome, red peony root, safflower, etc. and medicine carrier as matrix.

Description

technical field [0001] The present invention relates to a medicine that has the functions of promoting qi and activating blood, relieving stagnation and blood stasis, nourishing blood and dredging channels, and is used for cardiovascular and cerebrovascular diseases such as coronary heart disease, arteriosclerosis, cor pulmonale, multiple infarct dementia, etc. A pharmaceutical composition for the treatment of headache, dizziness, chest pain, palpitations, etc., especially related to the preparation of extracts containing seven active ingredients of traditional Chinese medicines such as Danshen, Chuanxiong, Radix Paeoniae Rubra, Safflower, Rhizoma Cyperi, Woody Fragrance, and Hawthorn as raw materials A kind of pharmaceutical composition oral drop pill preparation. Background technique [0002] According to the ministerial drug standard WS 3 - Lemai granule prepared by the preparation method given in B-2308-97 is a kind of qi and blood circulation, relieving stagnation and ...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61P9/10
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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