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Chuanluotong drip pill used for suppressing cough and calming panting and its preparation method

A technology for bronchial asthma and emphysema, which is applied in the field of Chuanluotong dripping pills for relieving cough and asthma and its preparation, which can solve the problems that are not conducive to improving the ability of patients to seek medical treatment, the bioavailability of the first-pass effect of the liver and intestines, and the overall health level and other issues, to achieve the effect of improving bioavailability, drug safety, and high degree of automation

Inactive Publication Date: 2005-10-26
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
[0008] In addition, conventional oral dosage forms, such as tablets, capsules, granules (infusions), etc., due to the granulation process in the preparation process, will generate relatively large dust pollution, which will cause health problems to the staff to a certain extent. harm, and also cause some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0031] Now with several groups of specific examples, the preparation method of Chuanluotong dripping pills of the present invention will be further described.

[0032] Group 1: Tests with a single matrix

[0033] 1. Raw materials: According to the [Appendix], the dry powder of the active ingredient extracts of 11 traditional Chinese medicines, such as chicken root, golden buckwheat, ginseng, purple river car, gecko, earthworm, toad venom, fritillary fritillaria, ephedra, bitter almond, licorice, etc., was first prepared for later use ;

[0034] 2. Substrate: polyethylene glycol 1000 , polyethylene glycol 4000 , polyethylene glycol 6000 , polyethylene glycol 10000 , polyethylene glycol 20000 , Span 40, Tween 80, polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate , glycerin gelatin, shellac;

[0035] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[003...

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PUM

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Abstract

A Chinese medicine in the form of dripping pill for treating cough and asthma is prepared from 11 Chinese-medicinal materials including ginseng, human placenta, earthworm, liquorice root, etc. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to a pharmaceutical composition which has the functions of benefiting the lung and strengthening the kidney, relieving cough and relieving asthma, and is used for the treatment of diseases such as consumptive chronic cough, bronchial asthma and emphysema. An oral preparation of a pharmaceutical composition prepared from active ingredient extracts of 11 traditional Chinese medicines such as river car, gecko, earthworm, toad venom, fritillary fritillaria, ephedra, bitter almond, and licorice. Background technique [0002] Chuanluotong Capsules, prepared according to the preparation method given in the national drug standard WS-10117 (ZD-0117)-2002, is a medicine that has the effects of nourishing the lungs and kidneys, relieving cough and asthma, and is used for chronic cough due to fatigue and Oral capsule preparations for the treatment of bronchial asthma, emphysema and other diseases have been clinically verified and have definit...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/583A61K35/62A61K35/65
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司